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Michael M. Hoffman

Researcher at Princess Margaret Cancer Centre

Publications -  71
Citations -  14816

Michael M. Hoffman is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Genome & Chromatin. The author has an hindex of 28, co-authored 65 publications receiving 12614 citations. Previous affiliations of Michael M. Hoffman include University of Texas at Austin & University of Toronto.

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An integrated encyclopedia of DNA elements in the human genome

Ian Dunham, +442 more
TL;DR: The Encyclopedia of DNA Elements project provides new insights into the organization and regulation of the authors' genes and genome, and is an expansive resource of functional annotations for biomedical research.
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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

LaDeana W. Hillier, +174 more
- 09 Dec 2004 - 
TL;DR: A draft genome sequence of the red jungle fowl, Gallus gallus, provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes.
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ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

TL;DR: This work discusses how ChIP quality, assessed in these ways, affects different uses of ChIP-seq data and develops a set of working standards and guidelines for ChIP experiments that are updated routinely.
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Opportunities and obstacles for deep learning in biology and medicine.

TL;DR: It is found that deep learning has yet to revolutionize biomedicine or definitively resolve any of the most pressing challenges in the field, but promising advances have been made on the prior state of the art.
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A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

Richard M. Myers, +328 more
- 01 Apr 2011 - 
TL;DR: An overview of the project and the resources it is generating and the application of ENCODE data to interpret the human genome are provided.