H
Harvey J. Grill
Researcher at University of Pennsylvania
Publications - 172
Citations - 15156
Harvey J. Grill is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Leptin & Forebrain. The author has an hindex of 63, co-authored 168 publications receiving 13834 citations. Previous affiliations of Harvey J. Grill include Beth Israel Deaconess Medical Center & Rockefeller University.
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Journal ArticleDOI
The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats
Harvey J. Grill,Ralph Norgren +1 more
TL;DR: These normative data for the intact rat can be directly compared to the taste reactivity of neurally ablated preparations which do not spontaneously feed or drink and can be utlized in determining the neural substrates necessary for the execution and regulation of ingestive behavior.
Journal ArticleDOI
Glucagon-like peptide 1 (GLP-1)
Timo D. Müller,Brian Finan,Stephen R. Bloom,David A. D'Alessio,Daniel J. Drucker,Peter R. Flatt,Andreas Fritsche,Fiona M. Gribble,Harvey J. Grill,Joel F. Habener,Jens J. Holst,Wolfgang Langhans,Juris J. Meier,Michael A. Nauck,Diego Perez-Tilve,Alessandro Pocai,Frank Reimann,Darleen A. Sandoval,Thue W. Schwartz,Randy J. Seeley,Kerstin Stemmer,Mads Tang-Christensen,Stephen C. Woods,Richard D. DiMarchi,M.H. Tschöp +24 more
TL;DR: The numerous beneficial effects of GLP-1 render this hormone an interesting candidate for the development of pharmacotherapies to treat obesity, diabetes, and neurodegenerative disorders.
Journal ArticleDOI
The taste reactivity test. II. Mimetic responses to gustatory stimuli in chronic thalamic and chronic decerebrate rats
Harvey J. Grill,Ralph Norgren +1 more
TL;DR: Based on the similarities in the ingestion and rejection responses of decerebrate and intact rats, it appears that discriminative responses to taste result from integrative mechanisms complete within, or caudal to, the midbrain.
Journal ArticleDOI
Chronically decerebrate rats demonstrate satiation but not bait shyness.
TL;DR: Food-deprived decerebrate rats, like intact ones, ingested a taste substance they had rejected when sated, but these same decerebrates neither rejected nor decreased ingestive reactions to a novel taste after that taste had been repeatedly paired with lithium chloride-induced illness.
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Evidence That the Caudal Brainstem Is a Target for the Inhibitory Effect of Leptin on Food Intake
Harvey J. Grill,Michael W. Schwartz,Joel M. Kaplan,James S. Foxhall,John F. Breininger,Denis G. Baskin +5 more
TL;DR: The results indicate that the CBS contains neurons that are potentially direct targets for the action of leptin in the control of energy homeostasis.