H
Hediye Erdjument-Bromage
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 251
Citations - 80981
Hediye Erdjument-Bromage is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Histone code & Histone methyltransferase. The author has an hindex of 128, co-authored 240 publications receiving 76640 citations. Previous affiliations of Hediye Erdjument-Bromage include Kettering University.
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Journal ArticleDOI
Helix pomatia lectin, an inducer of Drosophila immune response, binds to hemomucin, a novel surface mucin.
Ulrich Theopold,Ulrich Theopold,Christos Samakovlis,Hediye Erdjument-Bromage,Natalie Dillon,B. Axelsson,Otto Schmidt,Paul Tempst,Dan Hultmark +8 more
TL;DR: The isolation and initial characterization of hemomucin is described, a novel Drosophila surface mucin that is likely to be involved in the induction of antibacterial effector molecules after binding a snail lectin.
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NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney disease
Thomas L. Nickolas,Catherine S. Forster,Meghan E. Sise,Nicholas Barasch,David Sola-Del Valle,Mélanie Viltard,Charles Buchen,Shlomo Kupferman,Maria Luisa Carnevali,Michael J. Bennett,Silvia Mattei,Achiropita Bovino,Lucia Argentiero,Andrea Magnano,Prasad Devarajan,Kiyoshi Mori,Hediye Erdjument-Bromage,Paul Tempst,Landino Allegri,Jonathan Barasch +19 more
TL;DR: Monospecific assays of the NGAL monomer demonstrated a correlation with histology that typifies progressive, severe CKD, and immunoreactivity of urinary neutrophil gelatinase-associated lipocalin in CKD was defined.
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Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.
TL;DR: The results suggest that Thp1p-Sac3p and Nab2p are functionally related heterogeneous nuclear ribonucleoproteins that define a further link between mRNA metabolism and transcription.
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Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1α/LRP130 complex
Marcus P. Cooper,Lishu Qu,Lindsay M. Rohas,Jiandie D. Lin,Wenli Yang,Hediye Erdjument-Bromage,Paul Tempst,Bruce M. Spiegelman +7 more
TL;DR: It is shown that LRP130 is a component of the PGC-1alpha (peroxisome proliferator-activated receptor coactivator 1-alpha) transcriptional coactivators holocomplex and regulates expression of PEPCK (phosphoenolpyruvate carboxykinase), G6P (glucose-6-phosphatase), and certain mitochondrial genes through PGC -1alpha.
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Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.
TL;DR: This work identifies a unique class of human kinase-activating subunits that may be functionally analagous to cyclins and indicates that each kinase may serve distinct functions.