H
Hong Ma
Researcher at University of California, Berkeley
Publications - 6
Citations - 781
Hong Ma is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Ubiquitin ligase complex & Gene. The author has an hindex of 4, co-authored 6 publications receiving 386 citations. Previous affiliations of Hong Ma include Peking University.
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Journal ArticleDOI
Comparative genetic architectures of schizophrenia in East Asian and European populations
Max Lam,Chia-Yen Chen,Zhiqiang Li,Alicia R. Martin,Alicia R. Martin,Julien Bryois,Xixian Ma,Helena Gaspar,Masashi Ikeda,Beben Benyamin,Beben Benyamin,Brielin C. Brown,Ruize Liu,Ruize Liu,Wei Zhou,Lili Guan,Yoichiro Kamatani,Sung-Wan Kim,Michiaki Kubo,Agung A.A.A Kusumawardhani,Chih-Min Liu,Hong Ma,Sathish Periyasamy,Atsushi Takahashi,Zhida Xu,Hao Yu,Feng Zhu,Wei J. Chen,Stephen V. Faraone,Stephen J. Glatt,Lin He,Lin He,Steven E. Hyman,Steven E. Hyman,Hai-Gwo Hwu,Steven A. McCarroll,Steven A. McCarroll,Benjamin M. Neale,Benjamin M. Neale,Pamela Sklar,Dieter B. Wildenauer,Xin Yu,Dai Zhang,Bryan J. Mowry,Jimmy Lee,Peter Holmans,Shuhua Xu,Patrick F. Sullivan,Stephan Ripke,Stephan Ripke,Stephan Ripke,Michael Conlon O'Donovan,Mark J. Daly,Shengying Qin,Shengying Qin,Pak C. Sham,Pak C. Sham,Nakao Iwata,Kyung Sue Hong,Sibylle G. Schwab,Sibylle G. Schwab,Weihua Yue,Ming T. Tsuang,Jianjun Liu,Jianjun Liu,Xiancang Ma,René S. Kahn,Yongyong Shi,Hailiang Huang,Hailiang Huang +69 more
TL;DR: The largest study to date of East Asian participants is reported, identifying 21 genome-wide-significant associations in 19 genetic loci associated with schizophrenia and highlighting the importance of including sufficient samples of major ancestral groups to ensure their generalizability across populations.
Journal ArticleDOI
Discovery of stimulation-responsive immune enhancers with CRISPR activation
Dimitre R. Simeonov,Benjamin G. Gowen,Mandy Boontanrart,Theodore L. Roth,John D. Gagnon,Maxwell R. Mumbach,Ansuman T. Satpathy,Youjin Lee,Youjin Lee,Nicolas Bray,Alice Y. Chan,Dmytro Lituiev,Michelle L.T. Nguyen,Michelle L.T. Nguyen,Rachel E. Gate,Meena Subramaniam,Zhongmei Li,Zhongmei Li,Jonathan M. Woo,Jonathan M. Woo,Therese Mitros,Graham J. Ray,Gemma L. Curie,Nicki Naddaf,Julia S. Chu,Hong Ma,Eric Boyer,Eric Boyer,Frédéric Van Gool,Hailiang Huang,Hailiang Huang,Ruize Liu,Ruize Liu,Victoria Tobin,Victoria Tobin,Kathrin Schumann,Kathrin Schumann,Mark J. Daly,Mark J. Daly,Kyle Kai-How Farh,K. Mark Ansel,Chun Jimmie Ye,William J. Greenleaf,Mark S. Anderson,Jeffrey A. Bluestone,Howard Y. Chang,Jacob E. Corn,Alexander Marson +47 more
TL;DR: A discovery platform that can identify stimulus-responsive enhancers for a target gene independent of stimulus exposure is described and reveals how non-coding variation associated with human immune dysfunction alters context-specific gene programs.
Posted ContentDOI
Comparative Genetic Architectures of Schizophrenia in East Asian and European Populations
Max Lam,Chia-Yen Chen,Zhiqiang Li,Xixian Ma,Helena Gaspar,Masashi Ikeda,Beben Benyamin,Brielin C. Brown,Ruize Liu,Wei Zhou,Lili Guan,Yoichiro Kamatani,Sung-Wan Kim,Michiaki Kubo,Agung A.A.A Kusumawardhani,Chih-Min Liu,Hong Ma,Sathish Periyasamy,Atsushi Takahashi,Qiang Wang,Zhida Xu,Hao Yu,Feng Zhu,Wei J. Chen,Stephen V. Faraone,Stephen J. Glatt,Lin He,Steven E. Hyman,Hai-Gwo Hwu,Tao Li,Steven A. McCarroll,Benjamin M. Neale,Pamela Sklar,Dieter B. Wildenauer,Xin Yu,Dai Zhang,Bryan J. Mowry,Jimmy Lee,Peter Holmans,Shuhua Xu,Patrick F. Sullivan,Stephan Ripke,Michael Conlon O'Donovan,Mark J. Daly,Shengying Qin,Pak C. Sham,Nakao Iwata,Kyung Sue Hong,Sibylle G. Schwab,Weihua Yue,Ming T. Tsuang,Jianjun Liu,Xiancang Ma,René S. Kahn,Yongyong Shi,Hailiang Huang,Alicia R. Martin,Julien Bryois +57 more
Journal ArticleDOI
The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells
Shaheen Kabir,Shaheen Kabir,Justin Cidado,Courtney L. Andersen,Cortni Dick,Pei-Chun Lin,Therese Mitros,Hong Ma,Seung Hyun Baik,Matthew A. Belmonte,Lisa Drew,Jacob E. Corn +11 more
TL;DR: Levels of the BH3-only pro-apoptotic proteins Bim and Noxa are proteasomally regulated by the CRL5 complex, which suggests the potential to improve combination treatments.
Posted ContentDOI
The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells
Jacob E. Corn,Shaheen Kabir,Justin Cidado,Courtney L. Andersen,Cortni Dick,Pei-Chun Lin,Therese Mitros,Hong Ma,Seung Hyun Baik,Matthew A. Belmonte,Lisa Drew +10 more
TL;DR: Discovery of a novel role of CRL5 in apoptosis and resistance to MCL1 inhibitors exposes new drug targets and the potential to improve combination treatments.