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Imre Kacskovics
Researcher at Eötvös Loránd University
Publications - 74
Citations - 2822
Imre Kacskovics is an academic researcher from Eötvös Loránd University. The author has contributed to research in topics: Neonatal Fc receptor & Antibody. The author has an hindex of 30, co-authored 71 publications receiving 2594 citations. Previous affiliations of Imre Kacskovics include Hungarian Academy of Sciences & University of Iowa.
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Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling
Barna Dudok,László Barna,Marco Ledri,Szilárd I. Szabó,Eszter Szabadits,Balazs Pinter,Stephen G. Woodhams,Christopher M. Henstridge,Gyula Y. Balla,Gyula Y. Balla,Rita Nyilas,Csaba Varga,Sang-Hun Lee,Máté Matolcsi,Judit Cervenak,Imre Kacskovics,Masahiko Watanabe,Claudia Sagheddu,Miriam Melis,Marco Pistis,Ivan Soltesz,István Katona +21 more
TL;DR: It is found that axon terminals of perisomatically projecting GABAergic interneurons possessed increased CB1 receptor number, active-zone complexity and receptor/effector ratio compared with dendritically projecting interneURons, consistent with higher efficiency of cannabinoid signaling at somatic versus dendritic synapses.
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Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome
Csaba Fekete,Balázs Gereben,Márton Doleschall,John W. Harney,José Miguel Dora,Antonio C. Bianco,Sumit Sarkar,Zsolt Liposits,William M. Rand,Charles P. Emerson,Imre Kacskovics,P. Reed Larsen,Ronald M. Lechan +12 more
TL;DR: It is proposed that LPS or LPS-induced cytokines directly induce D2 mRNA in tanycytes and may suppress the hypothalamus-pituitary-thyroid axis by local feedback inhibition of hypophysiotropic TRH and/or TSH and contribute to the mechanism of central hypothyroidism associated with infection.
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ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.
Martin Vaeth,Jun Yang,Megumi Yamashita,Isabelle Zee,Miriam Eckstein,Camille Knosp,Ulrike Kaufmann,Péter K. Jani,Rodrigo S. Lacruz,Veit Flockerzi,Imre Kacskovics,Murali Prakriya,Stefan Feske +12 more
TL;DR: It is demonstrated that ORAi1 and Orai2 form heteromeric CRAC channels, in which ORAI2 fine-tunes the magnitude of SOCE to modulate immune responses.
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The piglet as a model for B cell and immune system development
John E. Butler,Kelly M. Lager,Igor Splichal,David L. Francis,Imre Kacskovics,Marek Sinkora,Nancy Wertz,Jishan Sun,Yiqiang Zhao,W.r. Brown,R. Dewald,S. Dierks,Serge Muyldermans,Joan K. Lunney,Paul B. McCray,C.s. Rogers,Michael J. Welsh,P. Navarro,F. Klobasa,F. Habe,J. Ramsoondar +20 more
TL;DR: The history of the development of the piglet as a model for antibody repertoire development is summarized, thus providing a framework to guide future investigators.
Journal ArticleDOI
Artiodactyl IgD: the missing link.
Yaofeng Zhao,Imre Kacskovics,Imre Kacskovics,Qiang Pan,David A. Liberles,Janos Geli,Scott K. Davis,Hodjattallah Rabbani,Lennart Hammarström +8 more
TL;DR: The cow, sheep, and pig Ig δ genes have been identified and shown to be transcriptionally active and deduced amino acid sequences from their cDNAs show that artiodactyl IgD H chains are structurally similar to human IgD.