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Jacky Wing Yip Lam

Researcher at Hong Kong University of Science and Technology

Publications -  698
Citations -  55632

Jacky Wing Yip Lam is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Polymer & Polymerization. The author has an hindex of 106, co-authored 619 publications receiving 44048 citations. Previous affiliations of Jacky Wing Yip Lam include University of Hong Kong & Shenzhen University.

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Long-term fluorescent cellular tracing by the aggregates of AIE bioconjugates.

TL;DR: A new type of fluorescence "turn-on" probe for tracing live cells over a long period of time by attaching a large number of tetraphenylethene labels to a chitosan (CS) chain that shows a unique aggregation-induced emission (AIE) behavior.
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Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics

TL;DR: A biocompatible molecule that functions as an ex situ monitor and an in situ inhibitor for protein fibrillation, using insulin as a model protein to monitor amyloidosis kinetics and inhibit fibril formation is developed.
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Clusterization-triggered emission: Uncommon luminescence from common materials

TL;DR: In this paper, a comprehensive theory of the through-space conjugation (TSC) for these chromophores is proposed, and various applications have been envisioned, for example in the areas of process monitoring, structural visualization, sensors, and probes.
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What makes efficient circularly polarised luminescence in the condensed phase: aggregation-induced circular dichroism and light emission

TL;DR: In this paper, a molecular functional material with high performance of circularly polarised luminescence (CPL) in the condensed phase was synthesized and thoroughly characterized, and it was shown that upon molecular aggregation, both the CD and fluorescence are simultaneously turned on, showing aggregation-induced CD and emission (AIE) effects.
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Protein detection and quantitation by tetraphenylethene-based fluorescent probes with aggregation-induced emission characteristics.

TL;DR: The possibility of utilizing the AIE effect for protein detection and quantification is explored using bovine serum albumin (BSA) as a model protein, with salt 3 being found to perform as a stable, sensitive, and selective bioprobe.