J
Jane Hawkey
Researcher at Monash University
Publications - 47
Citations - 1704
Jane Hawkey is an academic researcher from Monash University. The author has contributed to research in topics: Acinetobacter baumannii & Population. The author has an hindex of 15, co-authored 38 publications receiving 1151 citations. Previous affiliations of Jane Hawkey include University of Melbourne.
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Journal ArticleDOI
Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events
Vanessa K. Wong,Vanessa K. Wong,Stephen Baker,Stephen Baker,Stephen Baker,Derek Pickard,Julian Parkhill,Andrew J. Page,Nicholas A. Feasey,Robert A. Kingsley,Robert A. Kingsley,Nicholas R. Thomson,Nicholas R. Thomson,Jacqueline A. Keane,François-Xavier Weill,David J. Edwards,Jane Hawkey,Simon R. Harris,Alison E. Mather,Amy K. Cain,James Hadfield,Peter J. Hart,Nga Tran Vu Thieu,Elizabeth J. Klemm,Dafni A. Glinos,Robert F. Breiman,Robert F. Breiman,Robert F. Breiman,Conall H. Watson,Samuel Kariuki,Samuel Kariuki,Melita A. Gordon,Robert S. Heyderman,Chinyere K. Okoro,Jan Jacobs,Jan Jacobs,Octavie Lunguya,W. John Edmunds,Chisomo L. Msefula,José A. Chabalgoity,Mike Kama,Kylie Jenkins,Shanta Dutta,Florian Marks,Josefina Campos,Corinne N. Thompson,Corinne N. Thompson,Stephen K. Obaro,Calman A. MacLennan,Calman A. MacLennan,Calman A. MacLennan,Christiane Dolecek,Karen H. Keddy,Anthony M. Smith,Christopher M. Parry,Christopher M. Parry,Abhilasha Karkey,E. Kim Mulholland,James Campbell,James Campbell,Sabina Dongol,Buddha Basnyat,Muriel Dufour,Don Bandaranayake,Take Toleafoa Naseri,Shalini Singh,Mochammad Hatta,Paul N. Newton,Paul N. Newton,Robert S. Onsare,Lupeoletalalei Isaia,David A. B. Dance,David A. B. Dance,Viengmon Davong,Guy E. Thwaites,Guy E. Thwaites,Lalith Wijedoru,John A. Crump,Elizabeth de Pinna,Satheesh Nair,Eric J. Nilles,Duy Pham Thanh,Paul Turner,Paul Turner,Paul Turner,Sona Soeng,Mary Valcanis,Joan Powling,Karolina Dimovski,Geoff Hogg,Jeremy Farrar,Jeremy Farrar,Kathryn E. Holt,Gordon Dougan +93 more
TL;DR: This whole-genome sequence analysis of Salmonella enterica serovar Typhi identifies a single dominant MDR lineage, H58, that has emerged and spread throughout Asia and Africa over the last 30 years, and identifies numerous transmissions of H58.
Journal ArticleDOI
Genome-scale rates of evolutionary change in bacteria.
Sebastián Duchêne,Sebastián Duchêne,Kathryn E. Holt,François-Xavier Weill,Simon Le Hello,Jane Hawkey,David J. Edwards,Mathieu Fourment,Edward C. Holmes +8 more
TL;DR: The robustly estimated evolutionary rates spanned several orders of magnitude, from approximately 10−5 to 10−8 nucleotide substitutions per site year−1, and variation was negatively associated with sampling time, with this relationship best described by an exponential decay curve.
Journal ArticleDOI
ISMapper: identifying transposase insertion sites in bacterial genomes from short read sequence data
Jane Hawkey,Mohammad Hamidian,Ryan R. Wick,David J. Edwards,Helen Billman-Jacobe,Ruth M. Hall,Kathryn E. Holt +6 more
TL;DR: The utility of ISMapper was further demonstrated by profiling genome-wide IS6110 insertions in 138 publicly available Mycobacterium tuberculosis genomes, revealing lineage-specific insertions and multiple insertion hotspots.
Journal ArticleDOI
Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307.
Kelly L. Wyres,Jane Hawkey,Marit Andrea Klokkhammer Hetland,Aasmund Fostervold,Aasmund Fostervold,Ryan R. Wick,Louise M. Judd,Mohammad Hamidian,Benjamin P Howden,Iren Høyland Löhr,Kathryn E. Holt,Kathryn E. Holt +11 more
TL;DR: It is shown that ST307 emerged in the mid-1990s, is already globally distributed and is intimately associated with a conserved plasmid harbouring the blaCTX-M-15 ESBL gene and several other AMR determinants.
Journal ArticleDOI
Trycycler: consensus long-read assemblies for bacterial genomes
Ryan R. Wick,Louise M. Judd,Louise Cerdeira,Jane Hawkey,Guillaume Méric,Guillaume Méric,Ben Vezina,Kelly L. Wyres,Kathryn E. Holt,Kathryn E. Holt +9 more
TL;DR: In this article, the authors present a tool which produces a consensus assembly from multiple input assemblies of the same genome using manual intervention, which is not deterministic and requires multiple users to converge on similar assemblies.