J
Jennifer Chew
Researcher at University of California, Los Angeles
Publications - 23
Citations - 1353
Jennifer Chew is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Gene & Transcriptome. The author has an hindex of 9, co-authored 18 publications receiving 418 citations. Previous affiliations of Jennifer Chew include Wake Forest University.
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Journal ArticleDOI
A single-cell and spatially resolved atlas of human breast cancers.
Sunny Z. Wu,Sunny Z. Wu,Ghamdan Al-Eryani,Ghamdan Al-Eryani,Daniel L. Roden,Daniel L. Roden,Simon Junankar,Simon Junankar,Kate Harvey,Alma Andersson,Aatish Thennavan,Chenfei Wang,James R. Torpy,James R. Torpy,Nenad Bartonicek,Nenad Bartonicek,Taopeng Wang,Taopeng Wang,Ludvig Larsson,Dominik C. Kaczorowski,Neil I. Weisenfeld,Cedric Uytingco,Jennifer Chew,Zachary Bent,Chia-Ling Chan,Vikkitharan Gnanasambandapillai,Charles-Antoine Dutertre,Charles-Antoine Dutertre,Laurence Gluch,Mun N. Hui,Jane Beith,Andrew Parker,Andrew Parker,Elizabeth Robbins,Davendra Segara,Caroline Cooper,Caroline Cooper,Cindy Mak,Belinda Chan,Sanjay Warrier,Florent Ginhoux,Florent Ginhoux,Florent Ginhoux,Ewan K.A. Millar,Ewan K.A. Millar,Ewan K.A. Millar,Joseph E. Powell,Joseph E. Powell,Stephen R. Williams,X. Shirley Liu,Sandra A O'Toole,Elgene Lim,Elgene Lim,Elgene Lim,Joakim Lundeberg,Charles M. Perou,Alexander Swarbrick,Alexander Swarbrick +57 more
TL;DR: In this paper, a single-cell and spatially resolved transcriptomics analysis of human breast cancers is presented, which reveals recurrent neoplastic cell heterogeneity and heterotypic interactions play central roles in disease progression.
Journal ArticleDOI
Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.
Caleb A. Lareau,Fabiana M. Duarte,Fabiana M. Duarte,Jennifer Chew,Vinay K. Kartha,Vinay K. Kartha,Zach D Burkett,Andrew Kohlway,Dmitry K. Pokholok,Martin J. Aryee,Martin J. Aryee,Frank J. Steemers,Ronald Lebofsky,Jason D. Buenrostro,Jason D. Buenrostro +14 more
TL;DR: A high-quality (105 nuclear fragments per cell) droplet-microfluidics-based method for single-cell profiling of chromatin accessibility that enables rapid mapping of genome accessibility in hundreds of thousands of single cells.
Journal ArticleDOI
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex.
Kristen R. Maynard,Leonardo Collado-Torres,Lukas M. Weber,Cedric Uytingco,Brianna K. Barry,Stephen R. Williams,Joseph L. Catallini,Matthew N. Tran,Zachary Besich,Madhavi Tippani,Jennifer Chew,Yifeng Yin,Joel E. Kleinman,Thomas M. Hyde,Nikhil Rao,Stephanie C. Hicks,Keri Martinowich,Andrew E. Jaffe +17 more
TL;DR: This article used the 10x Genomics Visium platform to define the spatial topography of gene expression in the six-layered human dorsolateral prefrontal cortex and identified extensive layer-enriched expression signatures and refined associations to previous laminar markers.
Journal ArticleDOI
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
Kristen R. Maynard,Leonardo Collado Torres,Lukas M. Weber,Cedric Uytingco,Brianna K. Barry,Stephen R. Williams,Joseph L. Catallini,Matthew N. Tran,Zachary Besich,Madhavi Tippani,Jennifer Chew,Yifeng Yin,Thomas M. Hyde,Nikhil Rao,Stephanie C. Hicks,Keri Martinowich,Andrew E. Jaffe +16 more
Journal ArticleDOI
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Anoushka Joglekar,Andrey D. Prjibelski,Ahmed Mahfouz,Ahmed Mahfouz,Paul Collier,Susan Lin,Anna Katharina Schlusche,Jordan Marrocco,Stephen R. Williams,Bettina Haase,Ashley Hayes,Jennifer Chew,Neil I. Weisenfeld,Man Ying Wong,Alexander N. Stein,Simon A. Hardwick,Simon A. Hardwick,Toby Hunt,Qi Wang,Christoph Dieterich,Zachary Bent,Olivier Fedrigo,Steven A. Sloan,Davide Risso,Erich D. Jarvis,Erich D. Jarvis,Paul Flicek,Wenjie Luo,Geoffrey S. Pitt,Adam Frankish,August B. Smit,M. Elizabeth Ross,Hagen Tilgner +32 more
TL;DR: In this article, a single-cell investigation of differential isoform expression (DIE) between brain regions using singlecell long-read sequencing in mouse hippocampus and prefrontal cortex in 45 cell types at postnatal day 7 is presented.