J
Jens Bukh
Researcher at University of Copenhagen
Publications - 302
Citations - 22917
Jens Bukh is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 71, co-authored 270 publications receiving 21051 citations. Previous affiliations of Jens Bukh include Copenhagen University Hospital & Hvidovre Hospital.
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Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
TL;DR: A stable infectious molecular clone of strain H77 (genotype 1a) of hepatitis C virus (HCV) is constructed and injection of RNA transcripts from this consensus clone into the liver of a chimpanzee resulted in viral replication.
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Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization
Betty H. Robertson,G Myers,C Howard,T Brettin,Jens Bukh,B Gaschen,Takashi Gojobori,Geert Maertens,Masashi Mizokami,Omana V. Nainan,Sergey V. Netesov,K Nishioka,Peter Simmonds,D B Smith,Lieven Stuyver,Amy J. Weiner +15 more
TL;DR: A summary of the recommendations that were formulated for the purposes of unifying the nomenclature for hepatitis C virus (HCV), based upon guidelines of the International Committee on Virus Taxonomy (ICTV), and provides guidelines for the incorporation of sequence data into an HCV database that will be available to researchers through the internet.
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ICTV Virus Taxonomy Profile: Flaviviridae.
Peter Simmonds,Paul Becher,Jens Bukh,Ernest A. Gould,Gregor Meyers,Thomas P. Monath,A. Scott Muerhoff,Alexander G. Pletnev,Rebecca Rico-Hesse,B. Douglas Smith,Jack T. Stapleton +10 more
TL;DR: The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases that infect mammals and birds and many are important human and veterinary pathogens.
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At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide
TL;DR: The complete nucleotide sequence of the putative envelope 1 (E1) gene in 51 HCV isolates from around the world is determined and it is found that they could be grouped into at least 12 distinct genotypes, with important implications for HCV diagnosis and vaccine development.
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Sequence analysis of the 5' noncoding region of hepatitis C virus.
TL;DR: The nucleotide sequence of the 5' noncoding (NC) region of the hepatitis C virus (HCV) genome in 44 isolates from around the world was determined in this article.