J
Jens Bukh
Researcher at University of Copenhagen
Publications - 302
Citations - 22917
Jens Bukh is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 71, co-authored 270 publications receiving 21051 citations. Previous affiliations of Jens Bukh include Copenhagen University Hospital & Hvidovre Hospital.
Papers
More filters
Journal ArticleDOI
Evaluation of commercially available and in-house reverse transcription-PCR assays for detection of hepatitis G virus or GB virus C.
TL;DR: Analysis of the 5'NC and NS3 sequences amplified by RT-nested PCR demonstrated that all but two positive patients had unique HGV or GBV-C sequences.
Journal ArticleDOI
Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors.
Long V. Pham,Santseharay Ramirez,Thomas H. R. Carlsen,Yi-Ping Li,Judith M. Gottwein,Jens Bukh +5 more
TL;DR: Efficient infectious JFH1-based cultures with genotype 1b core-NS5A sequences of strains DH1, Con1, and J4 are developed and evaluated, showing the efficacy of clinically relevant NS3/4A protease and NS5A inhibitors against the novel genotypes 1b viruses, as well as against previously developed 1a viruses.
Journal ArticleDOI
Viremia, genetic heterogeneity, and immunity to hepatitis G/GB‐C virus in multiply transfused patients with thalassemia
TL;DR: HGV is associated with persistent viremia but not with significant biochemical evidence of liver damage, and there is some genetic heterogeneity among HGV isolates from thalassemia patients in Israel.
Journal ArticleDOI
5-HTTLPR and use of antidepressants after colorectal cancer including a meta-analysis of 5-HTTLPR and depression after cancer.
Nis P. Suppli,Jens Bukh,Terrie E. Moffitt,Terrie E. Moffitt,Avshalom Caspi,Avshalom Caspi,Christoffer Johansen,Vanna Albieri,Anne Tjønneland,Lars Vedel Kessing,Susanne Oksbjerg Dalton +10 more
TL;DR: The findings in an original study and a meta-analysis do not support the hypothesis of an association between the 5-HTTLPR genotype and depression after cancer.
Posted ContentDOI
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
David A. Smith,Carlota Fernandez-Antunez,Andrea Magri,Rory Bowden,Nimisha Chaturvedi,Jacques Fellay,Jacques Fellay,Jacques Fellay,John McLauchlan,Graham R. Foster,William L. Irving,Peter Simmonds,V Pedergnana,Santseharay Ramirez,Jens Bukh,Eleanor Barnes,M A Ansari +16 more
TL;DR: The finding of polymorphisms in NS2 and NS3 proteins associated with poor treatment outcomes emphasises the value of more systematic genome-wide analyses of HCV in uncovering indirect but clinically relevant mechanisms of antiviral resistance.