Ekaterina Yonova-Doing

TL;DR: The CREAM consortium conducted genome-wide meta-analyses, which identified 16 new loci for refractive error in individuals of European ancestry and 8 were shared with Asians, and identified 8 additional associated loci.

TL;DR: Several novel genes influencing the major clinical risk predictors of POAG are identified and it is shown that genetic variation in CDKN1A is important in POAG risk.

TL;DR: The CREAM consortium conducted genome-wide meta-analyses, which identified 16 new loci for refractive error in individuals of European ancestry and 8 were shared with Asians, and identified 8 additional associated loci.

TL;DR: In this article , a cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses.

TL;DR: Genetic factors explained 35% of the variation in progression of nuclear cataract over a 10-year period and environmental factors accounted for the remaining variance, and in particular, dietary vitamin C protected againstCataract progression assessed approximately 10 years after baseline.