Jiang He

TL;DR: It is suggested that baseline serum GDF-15 could provide additional information to identify ischemic stroke patients at high risk of poor prognosis and the addition of G DF-15 to established risk factors improved risk prediction of the composite outcome of death and major disability.

TL;DR: In patients with CKD, the novel biomarker GDF-15, a marker of inflammation and tissue injury, and clinical biomarkers NT-proBNP and hsTnT, were associated with echocardiographic measurements of subclinical cardiovascular disease, suggesting these biomarkers may highlight biological pathways that contribute to the development of clinical HF.

TL;DR: This study has identified novel and important metabolites and metabolic networks associated with arterial stiffness and identified 2 modules associated with both AI and PWV.

TL;DR: Increasing FGF-23 levels are independently associated with increased risk for incident KRT, and membership in the slowly and rapidly increasing F GF-23 trajectory groups was associated with ∼3- and ∼21-fold higher risk for incidents.