Jie Zhou

TL;DR: The B.617.1.2 spike protein was able to mediate highly efficient syncytium formation that was less sensitive to inhibition by neutralizing antibody, compared with that of wild-type spike as discussed by the authors.

TL;DR: In this article, the authors show that the polybasic insertion of SARS-CoV-2 has a poly-basic insertion (PRRAR) at the S1/S2 cleavage site that can be cleaved by furin.

TL;DR: The authors develop a self-amplifying RNA encoding the SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle as a vaccine candidate and show induction of neutralization antibody titers in mice that are comparable to titer in convalescent sera of patients.

TL;DR: In this paper, the authors evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) surface and air contamination during the COVID-19 pandemic in London.

TL;DR: The findings of extensive viral RNA contamination of surfaces and air across a range of acute healthcare settings in the absence of cultured virus underlines the potential risk from environmental contamination in managing COVID-19, and the need for effective use of PPE, physical distancing, and hand/surface hygiene.