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John D. Gillece

Researcher at Translational Genomics Research Institute

Publications -  47
Citations -  2877

John D. Gillece is an academic researcher from Translational Genomics Research Institute. The author has contributed to research in topics: Population & Multilocus sequence typing. The author has an hindex of 23, co-authored 41 publications receiving 2257 citations.

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Population Genetics of Vibrio cholerae from Nepal in 2010: Evidence on the Origin of the Haitian Outbreak

TL;DR: Results in this study are consistent with Nepal as the origin of the Haitian outbreak, highlighting how rapidly infectious diseases might be transmitted globally through international travel and how public health officials need advanced molecular tools along with standard epidemiological analyses to quickly determine the sources of outbreaks.
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NASP: an accurate, rapid method for the identification of SNPs in WGS datasets that supports flexible input and output formats.

TL;DR: This study demonstrates how NASP compares with other tools in the analysis of two real bacterial genomics datasets and one simulated dataset and demonstrates differences in results based on the choice of the reference genome and choice of inferring phylogenies from concatenated SNPs or alignments including monomorphic positions.
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Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial

TL;DR: In this article , a bifidogenic live bacterial product (CBM588) was proposed to augment the response to checkpoint inhibitors through modulation of the gut microbiome, and the results showed that CBM588 appeared to enhance the clinical outcome in patients with metastatic renal cell carcinoma treated with nivolumab-ipilimumab.