J
Jun Cai
Researcher at Beijing Institute of Genomics
Publications - 66
Citations - 2696
Jun Cai is an academic researcher from Beijing Institute of Genomics. The author has contributed to research in topics: Density functional theory & Induced pluripotent stem cell. The author has an hindex of 23, co-authored 61 publications receiving 2498 citations. Previous affiliations of Jun Cai include Tsinghua University & East China University of Science and Technology.
Papers
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Journal ArticleDOI
A core Klf circuitry regulates self-renewal of embryonic stem cells
Jianming Jiang,Yun-Shen Chan,Yun-Shen Chan,Yuin-Han Loh,Yuin-Han Loh,Jun Cai,Guo-Qing Tong,Guo-Qing Tong,Ching-Aeng Lim,Ching-Aeng Lim,Paul Robson,Paul Robson,Sheng Zhong,Huck-Hui Ng,Huck-Hui Ng +14 more
TL;DR: This study provides new insight into how the core Klf circuitry integrates into the Nanog transcriptional network to specify gene expression that is unique to ES cells.
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Sperm, but Not Oocyte, DNA Methylome Is Inherited by Zebrafish Early Embryos
Lan Jiang,Jing Zhang,Jing-Jing Wang,Jing-Jing Wang,Lu Wang,Lu Wang,Li Zhang,Guoqiang Li,Guoqiang Li,Xiaodan Yang,Xin Ma,Xin Ma,Xin Sun,Jun Cai,Jun Zhang,Xingxu Huang,Miao Yu,Xuegeng Wang,Feng Liu,Chung-I Wu,Chuan He,Bo Zhang,Weimin Ci,Jiang Liu +23 more
TL;DR: Nine single-base resolution DNA methylomes are generated, including zebrafish gametes and early embryos, and it is shown that inheritance of the sperm methylome facilitates the epigenetic regulation of embryogenesis.
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Calculation of Wing Flutter by a Coupled Fluid-Structure Method
TL;DR: In this article, an integrated computational fluid dynamics (CFD) and computational structural dynamics (CSD) method is developed for the simulation and prediction of flutter, which is based on an unsteady, parallel, multiblock, multigrid finite volume algorithm for the Euler/Navier-Stokes equations.
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Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
Yong Tao,Jue Ruan,Shiou-Hwei Yeh,Xuemei Lu,Yu Wang,Weiwei Zhai,Jun Cai,Shaoping Ling,Qiang Gong,Zecheng Chong,Zhengzhong Qu,Qianqian Li,Jiang Liu,Jin Yang,Caihong Zheng,Changqing Zeng,Hurng-Yi Wang,Jing Zhang,Sheng-Han Wang,Lingtong Hao,Lili Dong,Wenjie Li,Min Sun,Wei Zou,Caixia Yu,Chaohua Li,Guojing Liu,Lan Jiang,Jin Xu,Huanwei Huang,Chunyan Li,Shuangli Mi,Bing Zhang,Baoxian Chen,Wenming Zhao,Songnian Hu,Shi-Mei Zhuang,Yang Shen,Suhua Shi,Christopher D. Brown,Kevin P. White,Ding-Shinn Chen,Pei-Jer Chen,Chung-I Wu,Chung-I Wu +44 more
TL;DR: By using a cell-population genetic definition, this approach identified three coding changes (CCNG1, P62, and an indel/fusion gene) as tumor driver mutations, functionally distinct from mutations that accumulated earlier, many of which are involved in inflammation/immunity or cell anchoring.
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An evaluation of cache invalidation strategies in wireless environments
TL;DR: This study shows that the two proposed schemes are not only effective in salvaging the cache content but consume significantly less energy than their counterparts.