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Chunyan Li
Researcher at Chinese Academy of Sciences
Publications - 40
Citations - 1067
Chunyan Li is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Oyster & Gene. The author has an hindex of 13, co-authored 38 publications receiving 809 citations. Previous affiliations of Chunyan Li include Beijing Institute of Genomics & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.
TL;DR: A systematic view of enhancer activity in diverse tumor contexts is provided and the clinical implications of enhancers are suggested, revealing enhancers of clinically actionable genes.
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Genome and transcriptome analyses provide insight into the euryhaline adaptation mechanism of Crassostrea gigas.
TL;DR: This study was the first to explain oyster euryhaline adaptation at a genome-wide scale in C. gigas, suggesting oyster’s powerful ability regarding FAAs metabolism, allowing it to adapt to fluctuating salinities, which may be one important mechanism underlying eury Haline adaption in oyster.
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Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
Yong Tao,Jue Ruan,Shiou-Hwei Yeh,Xuemei Lu,Yu Wang,Weiwei Zhai,Jun Cai,Shaoping Ling,Qiang Gong,Zecheng Chong,Zhengzhong Qu,Qianqian Li,Jiang Liu,Jin Yang,Caihong Zheng,Changqing Zeng,Hurng-Yi Wang,Jing Zhang,Sheng-Han Wang,Lingtong Hao,Lili Dong,Wenjie Li,Min Sun,Wei Zou,Caixia Yu,Chaohua Li,Guojing Liu,Lan Jiang,Jin Xu,Huanwei Huang,Chunyan Li,Shuangli Mi,Bing Zhang,Baoxian Chen,Wenming Zhao,Songnian Hu,Shi-Mei Zhuang,Yang Shen,Suhua Shi,Christopher D. Brown,Kevin P. White,Ding-Shinn Chen,Pei-Jer Chen,Chung-I Wu,Chung-I Wu +44 more
TL;DR: By using a cell-population genetic definition, this approach identified three coding changes (CCNG1, P62, and an indel/fusion gene) as tumor driver mutations, functionally distinct from mutations that accumulated earlier, many of which are involved in inflammation/immunity or cell anchoring.
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Divergence and plasticity shape adaptive potential of the Pacific oyster
Li Li,Ao Li,Kai Song,Jie Meng,Ximing Guo,Shiming Li,Chunyan Li,Pierre De Wit,Huayong Que,Fucun Wu,Wei Wang,Haigang Qi,Fei Xu,Cong Rihao,Baoyu Huang,Yingxiang Li,Ting Wang,Xueying Tang,Sheng Liu,Busu Li,Ruihui Shi,Youli Liu,Chen Bu,Chi Zhang,Weiming He,Shancen Zhao,Hongjun Li,Shoudu Zhang,Linlin Zhang,Guofan Zhang +29 more
TL;DR: It is shown that genetic divergence and plasticity contribute to local adaptation of Pacific oyster populations, suggesting that selection and local adaptation are pervasive and, together with limited gene flow, influence population structure.
Journal ArticleDOI
Construction and evaluation of a high-density SNP array for the Pacific oyster (Crassostrea gigas)
TL;DR: Carrying 133 K polymorphic SNPs, this oyster 190K SNP array is the first commercially available high-density SNP chip for mollusks, with the highest throughput.