Kamil Uludag

TL;DR: How in vivo locus coeruleus imaging can be used as a biomarker for noradrenergic dysfunction in neurodegenerative diseases is described and a strategy for achieving reliable and biologically validated imaging approaches is outlined.

TL;DR: A new cortical depth-dependent model of the BOLD response based on the principle of mass conservation is presented, which takes the effect of ascending (and pial) veins on the cortical BOLD responses explicitly into account and provides a conceptual framework for the biophysical interpretation of common experimental observations in high-resolution fMRI data.

TL;DR: Aerobic exercise training improves regional CBF in sedentary older men, which may underlie exercise-induced beneficial effects on executive function, which could be partly mediated by improvements in glucose metabolism.

TL;DR: Whole-brain layer-fMRI without large-vessel contamination is applicable for human neuroscience and opens the door to investigate biological mechanisms behind any number of psychological and psychiatric phenomena, such as selective attention, hallucinations and delusions, and even conscious perception.

TL;DR: The results indicate that Neuromelanin-MRI contrast in the LC likely results from a lower macromolecular fraction, thus facilitating interpretation of results in clinical populations, and demonstrate that in older individuals T1 lengthening occurs in theLC.