Kerrin Pine

TL;DR: How in vivo locus coeruleus imaging can be used as a biomarker for noradrenergic dysfunction in neurodegenerative diseases is described and a strategy for achieving reliable and biologically validated imaging approaches is outlined.

TL;DR: This paper reviews the methods and in-vivo MRI studies on the anatomical layers in the human cortex based on conventional and quantitative MRI (excluding diffusion imaging) and a focus is on the related challenges, promises and potential future developments.

TL;DR: Fast field-cycling magnetic resonance imaging (FFC-MRI) has a number of significant applications and advantages over conventional techniques, such as protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFCMRI with magnetisation transfer contrast as mentioned in this paper.

TL;DR: It is demonstrated that MR contrast in SWM is driven by iron and can be linked to the microscopic iron distribution, and laid the groundwork for systematic in vivo SWM mapping using ultrahigh resolution 7 T magnetic resonance imaging.

TL;DR: NODDI-DTI is demonstrated to be a promising model and technique to interpret restricted datasets acquired for DTI analysis in healthy white matter with greater biophysical specificity, though its limitations must be borne in mind.