K
Karenina Sanders
Researcher at University of California, San Diego
Publications - 20
Citations - 612
Karenina Sanders is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 8, co-authored 15 publications receiving 234 citations.
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Journal ArticleDOI
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans
Connie W.Y. Ha,Anthony Martin,Gregory D. Sepich-Poore,Baochen Shi,Yizhou Wang,Kenneth Gouin,Gregory Humphrey,Karenina Sanders,Yasiru Ratnayake,Kelvin S.L. Chan,Gustaf Hendrick,J.R. Caldera,Christian Arias,Jacob E. Moskowitz,Shannan J. Ho Sui,Shaohong Yang,David M. Underhill,Matthew J. Brady,Simon R.V. Knott,Kelly Kaihara,Michael J. Steinbaugh,Huiying Li,Dermot P.B. McGovern,Rob Knight,Phillip Fleshner,Suzanne Devkota +25 more
TL;DR: A subset of mucosal-associated gut bacteria that consistently translocated and remained viable in CrF in CD ileal surgical resections is discovered, and Clostridium innocuum is identified as a signature of this consortium with strain variation between mucosal and adipose isolates, suggesting preference for lipid-rich environments.
Journal ArticleDOI
The impact of skin care products on skin chemistry and microbiome dynamics
Amina Bouslimani,Ricardo Silva,Tomasz Kosciolek,Stefan Janssen,Stefan Janssen,Chris Callewaert,Chris Callewaert,Amnon Amir,Kathleen Dorrestein,Alexey V. Melnik,Livia S. Zaramela,Ji-Nu Kim,Gregory Humphrey,Tara Schwartz,Karenina Sanders,Caitriona Brennan,Tal Luzzatto-Knaan,Gail Ackermann,Daniel McDonald,Karsten Zengler,Rob Knight,Pieter C. Dorrestein +21 more
TL;DR: Findings may lead to next-generation precision beauty products and therapies for skin disorders, including alterations in steroid and pheromone levels and in bacterial and archaeal ecosystem structure and dynamics.
Journal ArticleDOI
Association Between the Gut Microbiota and Blood Pressure in a Population Cohort of 6953 Individuals.
Joonatan Palmu,Joonatan Palmu,Aaro Salosensaari,Aaro Salosensaari,Aki S. Havulinna,Susan Cheng,Michael Inouye,Michael Inouye,Mohit Jain,Rodolfo A. Salido,Karenina Sanders,Caitriona Brennan,Gregory Humphrey,Jon G. Sanders,Erkki Vartiainen,Tiina Laatikainen,Tiina Laatikainen,Pekka Jousilahti,Veikko Salomaa,Rob Knight,Leo Lahti,Teemu J. Niiranen,Teemu J. Niiranen +22 more
TL;DR: The associations between overall gut taxonomic composition and BP are weak, individuals with hypertension demonstrate changes in several genera, highlighting the need for experimental studies.
Journal ArticleDOI
Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads.
Jon G. Sanders,Sergey Nurk,Rodolfo A. Salido,Jeremiah J. Minich,Zhenjiang Zech Xu,Qiyun Zhu,Cameron Martino,Marcus W. Fedarko,Timothy D. Arthur,Feng Chen,Brigid S. Boland,Greg Humphrey,Caitriona Brennan,Karenina Sanders,James Gaffney,Kristen Jepsen,Mahdieh Khosroheidari,Cliff Green,Marlon Liyanage,Jason Dang,Vanessa V. Phelan,Robert A. Quinn,Robert A. Quinn,Anton Bankevich,John T. Chang,Tariq M. Rana,Douglas Conrad,William J. Sandborn,Larry Smarr,Pieter C. Dorrestein,Pieter C. Dorrestein,Pavel A. Pevzner,Rob Knight +32 more
TL;DR: A benchmark of library prep and sequencing using internal references generated by synthetic long-read technology is introduced, allowing us to evaluate high-throughput library preparation methods against gold-standard reference genomes derived from the samples themselves.
Journal ArticleDOI
Taxonomic signatures of cause-specific mortality risk in human gut microbiome
Aaro Salosensaari,Aaro Salosensaari,Ville Laitinen,Aki S. Havulinna,Guillaume Méric,Guillaume Méric,Susan Cheng,Susan Cheng,Markus Perola,Liisa Valsta,Georg Alfthan,Michael Inouye,Michael Inouye,Jeramie D. Watrous,Tao Long,Rodolfo A. Salido,Karenina Sanders,Caitriona Brennan,Gregory Humphrey,Jon G. Sanders,Mohit Jain,Pekka Jousilahti,Veikko Salomaa,Rob Knight,Leo Lahti,Teemu J. Niiranen +25 more
TL;DR: In this paper, the authors investigated the long-term association between gut microbiome variation and mortality in a well-phenotyped and representative population cohort from Finland and reported robust taxonomic and functional microbiome signatures related to the Enterobacteriaceae family that are associated with mortality risk during a 15-year follow-up.