Katina I. Spanier

TL;DR: A single-cell transcriptome atlas of the entire adult Drosophila melanogaster brain sampled across its lifespan is presented, allowing comprehensive exploration of all transcriptional states of an entire aging brain.

TL;DR: A single-cell atlas of the adult fly, Tabula Drosophilae, that includes 580,000 nuclei from 15 individually dissected sexed tissues as well as the entire head and body, annotated to >250 distinct cell types is presented, providing an in-depth analysis of cell type–related gene signatures and transcription factor markers, as as sexual dimorphism, across the whole animal.

TL;DR: Redundancy analysis showed a distinct and significant clustering of the gut microbiota of individuals consuming an AXOS diet, demonstrating a shift in the hindgut microbiome of fish consuming different preparation of AXOS, with potential application as prebiotics.

TL;DR: Analysis of melanoma cultures and large-scale gene expression analysis in patient samples indicate that an intermediate state exists and is driven by a distinct and stable ‘mixed’ GRN rather than being a symbiotic heterogeneous mix of cells.

TL;DR: The STRESSFLEA consortium generated a comprehensive RNA-Seq data set by exposing two inbred genotypes of D. magna and a recombinant cross of these genotypes to a range of environmental perturbations to investigate links between genes and the environment.