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Kedibone M. Ndlangisa
Researcher at University of the Witwatersrand
Publications - 12
Citations - 233
Kedibone M. Ndlangisa is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Serotype & Population. The author has an hindex of 5, co-authored 8 publications receiving 132 citations. Previous affiliations of Kedibone M. Ndlangisa include Medical Research Council & National Health Laboratory Service.
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Journal ArticleDOI
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Stephanie W. Lo,Rebecca A. Gladstone,Andries J. van Tonder,John A. Lees,Mignon du Plessis,Rachel Benisty,Noga Givon-Lavi,Paulina A. Hawkins,Jennifer E. Cornick,Brenda Kwambana-Adams,Brenda Kwambana-Adams,Pierra Y. Law,Pak-Leung Ho,Martin Antonio,Dean Everett,Ron Dagan,Anne von Gottberg,Keith P. Klugman,Lesley McGee,Robert F. Breiman,Stephen D. Bentley,Abdullah Brooks,Alejandra Corso,Alexander Davydov,Alison J. Maguire,Andrew J. Pollard,Anmol M. Kiran,Anna Skoczynska,Benild Moiane,Bernard Beall,Betuel Sigaúque,David M. Aanensen,Deborah Lehmann,Diego Faccone,Ebenezer Foster-Nyarko,Ebrima Bojang,Ekaterina Egorova,Elena Voropaeva,Eric Sampane-Donkor,Ewa Sadowy,Godfrey Bigogo,Helio Mucavele,Houria Belabbès,Idrissa Diawara,Jennifer C. Moïsi,Jennifer R. Verani,Jeremy D. Keenan,Jyothish N Nair Thulasee Bhai,Kedibone M. Ndlangisa,Khalid Zerouali,K L Ravikumar,Leonid Titov,Linda de Gouveia,Maaike Alaerts,Margaret Ip,Maria Cristina de Cunto Brandileone,Hasanuzzaman,Metka Paragi,Michele Nurse-Lucas,Mushal Ali,Naima Elmdaghri,Nicholas J. Croucher,Nicole Wolter,Nurit Porat,Ozgen Koseoglu Eser,Patrick Eberechi Akpaka,Paul Turner,Paula Gagetti,Peggy-Estelle Tientcheu,Philip E. Carter,Rafal Mostowy,Rama Kandasamy,Rebecca Ford,Rebecca Henderson,Roly Malaker,Sadia Shakoor,Samanta Cristine Grassi Almeida,Samir K. Saha,Sanjay Doiphode,Shabir A. Madhi,Shamala Devi Sekaran,Somporn Srifuengfung,Stephen K. Obaro,Stuart C. Clarke,Susan A. Nzenze,Tamara Kastrin,Theresa J. Ochoa,Veeraraghavan Balaji,Waleria Hryniewicz,Yulia Urban +89 more
TL;DR: In this paper, a whole-genome sequenced 3233 invasive pneumococcal disease isolates from laboratory-based surveillance programs in Hong Kong (n=78), Israel, South Africa, Malawi, Nigeria, The Gambia, and USA were collected from children younger than 3 years.
Journal ArticleDOI
Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates.
Rebecca A. Gladstone,Stephanie W. Lo,Richard Goater,Corin A. Yeats,Benjamin Taylor,James Hadfield,John A. Lees,Nicholas J. Croucher,A J van Tonder,Leon J. Bentley,F X Quah,Anne J. Blaschke,Nicole L Pershing,Carrie L. Byington,Veeraraghavan Balaji,Waleria Hryniewicz,Beutel Sigaùque,K L Ravikumar,Almeida Scg.,Theresa J. Ochoa,Pak-Leung Ho,M.A. Du Plessis,Kedibone M. Ndlangisa,Jennifer E. Cornick,Brenda Kwambana-Adams,Brenda Kwambana-Adams,Rachel Benisty,Susan A. Nzenze,Shabir A. Madhi,Paulina A. Hawkins,Andrew J. Pollard,Dean Everett,Martin Antonio,Ron Dagan,Keith P. Klugman,A. von Gottberg,Benjamin J. Metcalf,Yanping Li,Bernard Beall,Lesley McGee,Robert F. Breiman,David M. Aanensen,Stephen D. Bentley +42 more
TL;DR: This work prepared 12 country-specific phylogenetic snapshots, and international phylogenetic snapshot of 73 common Global Pneumococcal Sequence Clusters previously defined using PopPUNK, and presents them in Microreact, to increase dissemination of genomic insights to the wider community, without the need for specialist training.
Journal ArticleDOI
Population Snapshot of Streptococcus pneumoniae Causing Invasive Disease in South Africa Prior to Introduction of Pneumococcal Conjugate Vaccines
Kedibone M. Ndlangisa,Kedibone M. Ndlangisa,Kedibone M. Ndlangisa,Mignon du Plessis,Mignon du Plessis,Mignon du Plessis,Nicole Wolter,Nicole Wolter,Nicole Wolter,Linda de Gouveia,Linda de Gouveia,Keith P. Klugman,Keith P. Klugman,Anne von Gottberg,Anne von Gottberg,Anne von Gottberg,for Germs-Sa +16 more
TL;DR: Genotypes rarely reported in other parts of the world but common among some of the serotypes highlight the importance of the data as these genotypes may emerge post PCV introduction.
Journal ArticleDOI
Genomic analysis of nontypeable pneumococci causing invasive pneumococcal disease in South Africa, 2003-2013.
Thabo Mohale,Nicole Wolter,Mushal Allam,Kedibone M. Ndlangisa,Penny Crowther-Gibson,Mignon du Plessis,Anne von Gottberg +6 more
TL;DR: A variety of mutations within the capsular region of Group I NTPn, some of which may be responsible for the nontypeable phenotype, are identified.
Journal ArticleDOI
Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study
Stephanie W. Lo,Kate C. Mellor,Robert Cohen,Alba Redin Alonso,Sophie Belman,Narender Kumar,Paulina A. Hawkins,Rebecca A. Gladstone,Anne von Gottberg,Balaji Veeraraghavan,K L Ravikumar,Rama Kandasamy,Sir Andrew J Pollard,Samir K. Saha,Godfrey Bigogo,Martin Antonio,Brenda Kwambana-Adams,Shaper Mirza,Sadia Shakoor,Imran Nisar,Jennifer E. Cornick,Deborah Lehmann,Rebecca Ford,Betuel Sigaúque,Paul Turner,Jennifer C. Moïsi,Stephen K Obaro,Ron Dagan,Idrissa Diawara,Anna Skoczyńska,Hui Wang,Philip E. Carter,Keith P. Klugman,Gail L. Rodgers,Robert F. Breiman,Lesley McGee,Stephen D. Bentley,C. Muñoz Almagro,Emmanuelle Varon,W. Abdullah Brooks,Alejandra Corso,Alexander Davydov,Alison J. Maguire,Anmol M. Kiran,Benild Moiane,Bernard Beall,Chunjiang Zhao,David M. Aanensen,A. Everett,Diego Faccone,Ebenezer Foster-Nyarko,Ebrima Bojang,Ekaterina Egorova,Elena Voropaeva,Eric Sampane-Donkor,Ewa Sadowy,Geetha Nagaraj,Helio Mucavele,Houria Belabbes,Naima Elmdaghri,Jennifer R. Verani,Jeremy Keenan,John A. Lees,Jyothish N Nair Thulasee Bhai,Kedibone M. Ndlangisa,Khalid Zerouali,Leon J. Bentley,Leonid P. Titov,Linda de Gouveia,Maaike Alaerts,Margaret Ip,Maria Cristina de Cunto Brandileone,Hasanuzzaman Hasanuzzaman,Metka Paragi,Michele Nurse-Lucas,Mignon du Plessis,Mushal Allam Mohamed Alhaj Ali,Nicholas J. Croucher,Nicole Wolter,Noga Givon-Lavi,Nurith Porat,Özgen Köseog ÿlu Eser,Pak-Leung Ho,Patrick Eberechi Akpaka,Paula Gagetti,Peggy-Estelle Tientcheu,Pierra Y. Law,Rachel Benisty,Rafal Mostowy,Roly Malaker,Samanta Cristine Grassi Almeida,Sanjay Doiphode,Shabir A. Madhi,Shamala Devi Sekaran,Stuart Nelson Clarke,Somporn Srifuengfung,Susan A. Nzenze,Tamara Kastrin,Theresa J. Ochoa,Waleria Hryniewicz,Yulia Urban +100 more
TL;DR: In this article , a whole-genome sequencing was performed on a collection of serotype 24F pneumococci from asymptomatic colonisation and invasive disease isolates among individuals younger than 18 years in France, from 2003 to 2018.