M
Maaike Alaerts
Researcher at University of Antwerp
Publications - 54
Citations - 1122
Maaike Alaerts is an academic researcher from University of Antwerp. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 14, co-authored 42 publications receiving 762 citations. Previous affiliations of Maaike Alaerts include Flanders Institute for Biotechnology & Malawi-Liverpool-Wellcome Trust Clinical Research Programme.
Papers
More filters
Journal ArticleDOI
Differences in manifestations of Marfan syndrome, Ehlers-Danlos syndrome, and Loeys-Dietz syndrome.
Josephina A.N. Meester,Aline Verstraeten,Dorien Schepers,Maaike Alaerts,Lut Van Laer,Bart Loeys,Bart Loeys +6 more
TL;DR: Many phenotypic features show overlap between the different subtypes of heritable connective tissue disorders, which makes the clinical diagnosis rather difficult and highlights the importance of molecular diagnostic confirmation.
Journal ArticleDOI
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Stephanie W. Lo,Rebecca A. Gladstone,Andries J. van Tonder,John A. Lees,Mignon du Plessis,Rachel Benisty,Noga Givon-Lavi,Paulina A. Hawkins,Jennifer E. Cornick,Brenda Kwambana-Adams,Brenda Kwambana-Adams,Pierra Y. Law,Pak-Leung Ho,Martin Antonio,Dean Everett,Ron Dagan,Anne von Gottberg,Keith P. Klugman,Lesley McGee,Robert F. Breiman,Stephen D. Bentley,Abdullah Brooks,Alejandra Corso,Alexander Davydov,Alison J. Maguire,Andrew J. Pollard,Anmol M. Kiran,Anna Skoczynska,Benild Moiane,Bernard Beall,Betuel Sigaúque,David M. Aanensen,Deborah Lehmann,Diego Faccone,Ebenezer Foster-Nyarko,Ebrima Bojang,Ekaterina Egorova,Elena Voropaeva,Eric Sampane-Donkor,Ewa Sadowy,Godfrey Bigogo,Helio Mucavele,Houria Belabbès,Idrissa Diawara,Jennifer C. Moïsi,Jennifer R. Verani,Jeremy D. Keenan,Jyothish N Nair Thulasee Bhai,Kedibone M. Ndlangisa,Khalid Zerouali,K L Ravikumar,Leonid Titov,Linda de Gouveia,Maaike Alaerts,Margaret Ip,Maria Cristina de Cunto Brandileone,Hasanuzzaman,Metka Paragi,Michele Nurse-Lucas,Mushal Ali,Naima Elmdaghri,Nicholas J. Croucher,Nicole Wolter,Nurit Porat,Ozgen Koseoglu Eser,Patrick Eberechi Akpaka,Paul Turner,Paula Gagetti,Peggy-Estelle Tientcheu,Philip E. Carter,Rafal Mostowy,Rama Kandasamy,Rebecca Ford,Rebecca Henderson,Roly Malaker,Sadia Shakoor,Samanta Cristine Grassi Almeida,Samir K. Saha,Sanjay Doiphode,Shabir A. Madhi,Shamala Devi Sekaran,Somporn Srifuengfung,Stephen K. Obaro,Stuart C. Clarke,Susan A. Nzenze,Tamara Kastrin,Theresa J. Ochoa,Veeraraghavan Balaji,Waleria Hryniewicz,Yulia Urban +89 more
TL;DR: In this paper, a whole-genome sequenced 3233 invasive pneumococcal disease isolates from laboratory-based surveillance programs in Hong Kong (n=78), Israel, South Africa, Malawi, Nigeria, The Gambia, and USA were collected from children younger than 3 years.
Journal ArticleDOI
Marfan Syndrome and Related Disorders: 25 Years of Gene Discovery.
TL;DR: The focus of the developing pharmacological treatment strategies is shifting from hemodynamic stress management to TGF‐β antagonism, and insights that have been gained in the molecular biology of MFS and related disorders over the past 25 years are discussed.
Journal ArticleDOI
A mutation update on the LDS‐associated genes TGFB2/3 and SMAD2/3
Dorien Schepers,Giada Tortora,Giada Tortora,Hiroko Morisaki,Gretchen MacCarrick,Mark E. Lindsay,David Liang,Sarju G. Mehta,Jennifer Hague,Judith M.A. Verhagen,Ingrid M.B.H. van de Laar,Marja W. Wessels,Y. Detisch,Mieke M. van Haelst,Annette F. Baas,Klaske D. Lichtenbelt,Kees P.J. Braun,Denise van der Linde,Jolien W. Roos-Hesselink,George McGillivray,Josephina A.N. Meester,Isabelle Maystadt,Paul Coucke,Elie El-Khoury,Sandhya Parkash,Birgitte Rode Diness,Lotte Risom,Ingrid Scurr,Yvonne Hilhorst-Hofstee,Takayuki Morisaki,Julie Richer,Julie Désir,Marlies Kempers,Andrea L. Rideout,Gabrielle Horne,Christopher P. Bennett,Elisa Rahikkala,Geert Vandeweyer,Maaike Alaerts,Aline Verstraeten,Hal Dietz,Lut Van Laer,Bart Loeys,Bart Loeys +43 more
TL;DR: The clinical manifestations of LDS clearly indicates that LDS concerns a disorder with a broad phenotypical spectrum that is still emerging as more patients will be identified, and the role of disturbed TGF‐β signaling in LDS pathogenesis is emphasized.
Journal ArticleDOI
Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor
Elisabeth Gillis,Ajay Anand Kumar,Ilse Luyckx,Christoph Preuss,Elyssa Cannaerts,Gerarda van de Beek,Björn Wieschendorf,Maaike Alaerts,Nikhita Ajit Bolar,Geert Vandeweyer,Josephina A.N. Meester,Florian Wünnemann,Russell A. Gould,Rustam Zhurayev,Zerbino Dd,Salah A. Mohamed,Seema Mital,Luc Mertens,Hanna M. Björck,Anders Franco-Cereceda,Andrew S. McCallion,Lut Van Laer,Judith M.A. Verhagen,Ingrid M.B.H. van de Laar,Marja W. Wessels,Emmanuel Messas,Guillaume Goudot,Michaela Nemcikova,Alice Krebsová,Marlies Kempers,Simone Salemink,Toon Duijnhouwer,Xavier Jeunemaitre,Juliette Albuisson,Per Eriksson,Gregor Andelfinger,Harry C. Dietz,Harry C. Dietz,Aline Verstraeten,Bart Loeys,Bart Loeys +40 more
TL;DR: A significant contribution of SMAD6 mutations to the etiology of the BAV/TAA phenotype is reported.