K
Kevin M. Joines
Researcher at Allen Institute for Brain Science
Publications - 3
Citations - 2443
Kevin M. Joines is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Biotinylated dextran amine & Adeno-associated virus. The author has an hindex of 3, co-authored 3 publications receiving 1864 citations.
Papers
More filters
Journal ArticleDOI
A mesoscale connectome of the mouse brain
Seung Wook Oh,Julie A. Harris,Lydia Ng,Brent Winslow,Nicholas Cain,Stefan Mihalas,Quanxin Wang,Chris Lau,Leonard Kuan,Alex M. Henry,Marty Mortrud,Benjamin Ouellette,Thuc Nghi Nguyen,Staci A. Sorensen,Clifford R. Slaughterbeck,Wayne Wakeman,Yang Li,David Feng,Anh Ho,Eric Nicholas,Karla E. Hirokawa,Phillip Bohn,Kevin M. Joines,Hanchuan Peng,Michael Hawrylycz,John W. Phillips,John G. Hohmann,Paul Wohnoutka,Charles R. Gerfen,Christof Koch,Amy Bernard,Chinh Dang,Allan R. Jones,Hongkui Zeng +33 more
TL;DR: A brain-wide, cellular-level, mesoscale connectome for the mouse, using enhanced green fluorescent protein-expressing adeno-associated viral vectors to trace axonal projections from defined regions and cell types, and high-throughput serial two-photon tomography to image the EGFP-labelled axons throughout the brain.
Journal ArticleDOI
An anatomic transcriptional atlas of human glioblastoma
Ralph B. Puchalski,Nameeta Shah,Jeremy A. Miller,Rachel A. Dalley,Steve R. Nomura,Jae Guen Yoon,Kimberly A. Smith,Michael Lankerovich,Darren Bertagnolli,Kris Bickley,Andrew F. Boe,Krissy Brouner,Stephanie Butler,Shiella Caldejon,Mike Chapin,Suvro Datta,Nick Dee,Tsega Desta,Tim A. Dolbeare,Nadezhda Dotson,Amanda Ebbert,David Feng,Xu Feng,Michael S. Fisher,Garrett Gee,Jeff Goldy,Lindsey Gourley,Benjamin W. Gregor,Guangyu Gu,Nika Hejazinia,John G. Hohmann,Parvinder Hothi,Robert Howard,Kevin M. Joines,Ali Kriedberg,Leonard Kuan,Chris Lau,Felix Lee,Hwahyung Lee,Tracy Lemon,Fuhui Long,Naveed Mastan,Erika Mott,Chantal Murthy,Kiet Ngo,Eric Olson,Melissa Reding,Zack Riley,David Rosen,David Sandman,Nadiya V. Shapovalova,Clifford R. Slaughterbeck,Andrew Sodt,Graham Stockdale,Aaron Szafer,Wayne Wakeman,Paul Wohnoutka,Steven J. White,Don Marsh,Robert C. Rostomily,Robert C. Rostomily,Lydia Ng,Chinh Dang,Allan R. Jones,Bart Keogh,Haley Gittleman,Jill S. Barnholtz-Sloan,Patrick J. Cimino,Megha S Uppin,C. Dirk Keene,Farrokh Farrokhi,Justin D. Lathia,Michael E. Berens,Antonio Iavarone,Amy Bernard,Ed S. Lein,John W. Phillips,Steven Rostad,Charles Cobbs,Michael Hawrylycz,Greg Foltz +80 more
TL;DR: The Ivy Glioblastoma Atlas is presented, an anatomically based transcriptional atlas of human gliOBlastoma that aligns individual histologic features with genomic alterations and gene expression patterns, thus assigning molecular information to the most important morphologic hallmarks of the tumor.
Journal ArticleDOI
Systematic comparison of adeno-associated virus and biotinylated dextran amine reveals equivalent sensitivity between tracers and novel projection targets in the mouse brain.
Quanxin Wang,Alex M. Henry,Julie A. Harris,Seung Wook Oh,Kevin M. Joines,Julie Nyhus,Karla E. Hirokawa,Nick Dee,Marty Mortrud,Sheana Parry,Benjamin Ouellette,Shiella Caldejon,Amy Bernard,Allan R. Jones,Hongkui Zeng,John G. Hohmann +15 more
TL;DR: Results show that AAV has actions equivalent to those of BDA as an anterograde tracer and is suitable for analysis of neural circuitry throughout the mouse brain.