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Polly J. Bingley
Researcher at University of Bristol
Publications - 129
Citations - 13070
Polly J. Bingley is an academic researcher from University of Bristol. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 50, co-authored 128 publications receiving 11997 citations. Previous affiliations of Polly J. Bingley include Southmead Hospital & University of Cambridge.
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Journal ArticleDOI
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
H Ueda,Howson Jmm.,Laura Esposito,Joanne M. Heward,Hywel Snook,Giselle Chamberlain,Dan Rainbow,Hunter Kmd.,Anne Smith,G Di Genova,G Di Genova,Mathias H. Herr,Mathias H. Herr,Ingrid Dahlman,Ingrid Dahlman,F Payne,Deborah J. Smyth,Christopher E. Lowe,Twells Rcj.,Sarah Howlett,Barry C. Healy,Sarah Nutland,Helen E. Rance,Vincent H. Everett,Luc J. Smink,A C Lam,Heather J. Cordell,Neil Walker,C Bordin,John S. Hulme,Costantino Motzo,Francesco Cucca,J F Hess,Michael L. Metzker,Michael L. Metzker,Jane Rogers,Simon G. Gregory,Amit Allahabadia,Amit Allahabadia,R Nithiyananthan,Eva Tuomilehto-Wolf,Jaakko Tuomilehto,Polly J. Bingley,Kathleen M Gillespie,Dag E. Undlien,Kjersti S. Rønningen,Cristian Guja,Constantin Ionescu-Tirgoviste,David A. Savage,Alexander P. Maxwell,Dennis Carson,Christopher Patterson,Jayne A. Franklyn,David Clayton,Laurence B. Peterson,Linda S. Wicker,John A. Todd,Gough Scl. +57 more
TL;DR: In this article, the authors identify polymorphisms of the cytotoxic T lymphocyte antigen 4 gene (CTLA4) as candidates for primary determinants of risk of the common autoimmune disorders Graves' disease, autoimmune hypothyroidism and type 1 diabetes.
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Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes
Susan P. Laing,Anthony J. Swerdlow,S.D. Slater,Andrew C Burden,Andrew D. Morris,N.R. Waugh,W. Gatling,Polly J. Bingley,Christopher Patterson +8 more
TL;DR: The risk of mortality from ischaemic heart disease is exceptionally high in young adult women with Type 1 diabetes, with rates similar to those in men with Type 2 diabetes under the age of 40, and the need to identify and treat coronary risk factors in these young patients is emphasised.
Journal ArticleDOI
Prediction of IDDM in the General Population: Strategies Based on Combinations of Autoantibody Markers
Polly J. Bingley,Ezio Bonifacio,Alistair J K Williams,Stefano Genovese,Gian Franco Bottazzo,Edwin A M Gale +5 more
TL;DR: Analysis of strategies based on detection of ≥2 antibodies with primary testing for GAD and IA-2 antibodies and second line testing for ICAs and/or IAAs suggests that antibody combinations can predict diabetes in the general population.
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Trends in childhood type 1 diabetes incidence in Europe during 1989-2008 : evidence of non-uniformity over time in rates of increase
Christopher Patterson,Éva Gyürüs,Joachim Rosenbauer,Ondrej Cinek,Andreas Neu,Edith Schober,Roger C Parslow,Geir Joner,Jannet Svensson,C. Castell,Polly J. Bingley,E. J. Schoenle,Przemysława Jarosz-Chobot,B. Urbonaite,Ulrike Rothe,Ciril Krzisnik,Constantin Ionescu-Tirgoviste,Ilse Weets,Mirjana Kocova,Gordana Stipančić,Mira Samardzic,C De Beaufort,Anders Green,Gisela Dahlquist,Gyula Soltész +24 more
TL;DR: The incidence rate of childhood type 1 diabetes continues to rise across Europe by an average of approximately 3–4% per annum, but the increase is not necessarily uniform, showing periods of less rapid and more rapid increase in incidence in some registers.
Journal ArticleDOI
The British Diabetic Association Cohort Study, I: all-cause mortality in patients with insulin-treated diabetes mellitus.
Susan P. Laing,Anthony J. Swerdlow,S.D. Slater,Johannes L. Botha,A C Burden,Norman R Waugh,A. W. M. Smith,R. D. Hill,Polly J. Bingley,Christopher Patterson,Z. Qiao,Harry Keen +11 more
TL;DR: This study aims to assess mortality in patients with diabetes incident under the age of 30 years by assessing the proportion of patients who die within a year of diagnosis of diabetes.