L
Lance D. Miller
Researcher at Wake Forest University
Publications - 208
Citations - 16169
Lance D. Miller is an academic researcher from Wake Forest University. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 58, co-authored 195 publications receiving 14459 citations. Previous affiliations of Lance D. Miller include University of Texas MD Anderson Cancer Center & East Carolina University.
Papers
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Journal ArticleDOI
Organoid Platform in Preclinical Investigation of Personalized Immunotherapy Efficacy in Appendiceal Cancer: Feasibility Study.
Steven Forsythe,Richard A Erali,Shyama Sasikumar,Preston Laney,Ethan Shelkey,Ralph B. D'Agostino,Lance D. Miller,Perry Shen,Edward A. Levine,Shay Soker,Konstantinos I. Votanopoulos +10 more
TL;DR: In this paper, the authors preclinically explore the application of immunotherapy in treating appendiceal cancer in a personalized organoid model and show that immunotherapy shows measurable efficacy in appendiceAL cancer organoids.
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Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center.
Ville Kytölä,Ville Kytölä,Ville Kytölä,Umit Topaloglu,Umit Topaloglu,Lance D. Miller,Lance D. Miller,Rhonda L. Bitting,Rhonda L. Bitting,Michael Goodman,Michael Goodman,Ralph D’ Agostino,Ralph D’ Agostino,Rodwige J. Desnoyers,Rodwige J. Desnoyers,Carol A. Albright,Carol A. Albright,George Yacoub,George Yacoub,Shadi Qasem,Shadi Qasem,Barry DeYoung,Barry DeYoung,Vesteinn Thorsson,Ilya Shmulevich,Meng Yang,Meng Yang,Meng Yang,Anastasia Shcherban,Anastasia Shcherban,Anastasia Shcherban,Matthew Pagni,Matthew Pagni,Liang Liu,Matti Nykter,Kexin Chen,Gregory A. Hawkins,Gregory A. Hawkins,Stefan C. Grant,Stefan C. Grant,W. Jeffrey Petty,W. Jeffrey Petty,Angela Tatiana Alistar,Angela Tatiana Alistar,Edward A. Levine,Edward A. Levine,Edgar D. Staren,Edgar D. Staren,Carl D. Langefeld,Vincent A. Miller,Gaurav Singal,Robin M. Petro,Robin M. Petro,Mac B. Robinson,William Blackstock,William Blackstock,Bayard L. Powell,Bayard L. Powell,Lynne I. Wagner,Lynne I. Wagner,Kristie L. Foley,Kristie L. Foley,Edward Abraham,Boris Pasche,Boris Pasche,Wei Zhang,Wei Zhang +66 more
TL;DR: Evidence is provided that tobacco is a major cause of genomic instability and heterogeneity in cancer, and TP53 mutations and key oncogene amplifications emerge as key factors contributing to cancer outcome disparities among different racial/ethnic groups.
Journal ArticleDOI
Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy.
Jing Su,Jing Su,Qianqian Song,Shadi Qasem,Stacey S O'Neill,Jingyun Lee,Cristina M. Furdui,Boris Pasche,Linda J. Metheny-Barlow,Adrianna H. Masters,Hui-Wen Lo,Fei Xing,Kounosuke Watabe,Lance D. Miller,Stephen B. Tatter,Adrian W. Laxton,Christopher T. Whitlow,Michael D. Chan,Michael H. Soike,Michael H. Soike,Jimmy Ruiz,Jimmy Ruiz +21 more
TL;DR: In this paper, a single institution retrospective collection of brain metastasis from patients who were diagnosed with lung, breast, and other primary tumors was sent for RNA sequencing, proteomic, and metabolomic analysis.
Journal ArticleDOI
Systems biology approach to studying proliferation-dependent prognostic subnetworks in breast cancer
Qianqian Song,Hongyan Wang,Jiguang Bao,Ashok K. Pullikuth,King C.P. Li,Lance D. Miller,Xiaobo Zhou +6 more
TL;DR: The findings indicate that certain biological networks underlying breast cancer metastasis differ in a proliferation-dependent manner and may form the basis of highly accurate prognostic classification models and have clinical utility in guiding therapeutic options for patients.
Journal ArticleDOI
Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation
Qiang Zhang,Meimei Wan,Jinming Shi,David A. Horita,Lance D. Miller,Timothy E. Kute,Steven J. Kridel,George Kulik,Guangchao Sui +8 more
TL;DR: It is demonstrated for the first time that YY 1 promotes mTORC2-mediated AKT activation and disrupting YY1-AKT interaction by OPB domain-based peptide may represent a potential strategy for cancer therapy.