Laura E Clark

TL;DR: Lower eGFR and more severe albuminuria independently predict mortality and ESRD among individuals selected for CKD, with the associations stronger for E SRD than for mortality.

TL;DR: Change in albuminuria was consistently associated with subsequent risk of end-stage kidney disease across a range of cohorts, lending support to the use of change inalbuminuria as a surrogate endpoint for end-Stage kidney disease in clinical trials of progression of chronic kidneys disease in the setting of increased album inuria.

TL;DR: This study demonstrates that hospital administrative comorbidity data compared moderately well with case note review data for cerebrovascular disease, ischaemic heart disease and diabetes, however there was significant under-recording of some otherComorbid conditions, and particularly common risk factors.

TL;DR: Clinical outcomes in a large British CKD cohort, identified through routine opportunistic testing, with a 6-year follow-up for renal replacement therapy initiation and death are explored, illustrating the difficulties for planning services.

TL;DR: Mortality in those with CKD is high, with non-cardiovascular diseases accounting for more than half of all deaths, and a mechanism to identify which patients may benefit from intervention to prevent cardiovascular disease or renal disease progression is needed.