Laurence D. Hurst

TL;DR: It is shown that synonymous sites in putative ESEs evolve more slowly than the remaining exonic sequence, and constraints on synonymous evolution within E SEs causes the true mutation rate to be underestimated by not more than approximately 8%.

TL;DR: This analysis suggests that the organization of global protein interaction network is highly interconnected and hence interdependent, more like the continuous dense aggregations of stratus clouds than the segregated configuration of altocumulus clouds.

TL;DR: It is hypothesized that persistently open chromatin domains are sinks for essential genes, as they enable reduced noise by avoidance of transcriptional bursting associated with chromatin remodeling, and concluded that different noise characteristics of different genomic domains favors nonrandom gene positioning.

TL;DR: Assayed the toxicity and adhesion of 90 MRSA (methicillin resistant S. aureus) isolates and found that while there was remarkably little variation in adhesion, toxicity varied by over an order of magnitude between isolates, suggesting different evolutionary selection pressures acting on these two traits.

TL;DR: It is demonstrated that within the brain Grb10 is expressed from the paternal allele from fetal life into adulthood and that ablation of this expression engenders increased social dominance specifically among other aspects of social behaviour, a finding supported by the observed increase in allogrooming by paternal Grb 10-deficient animals.