L
Lei Zhang
Researcher at Central South University
Publications - 694
Citations - 15023
Lei Zhang is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 51, co-authored 588 publications receiving 11345 citations. Previous affiliations of Lei Zhang include Monash University & Kirby Institute.
Papers
More filters
Journal ArticleDOI
Trends in and determinants of loss to follow up and early mortality in a rapid expansion of the antiretroviral treatment program in Vietnam: findings from 13 outpatient clinics.
TL;DR: To reduce early mortality, special attention is required to ensure timely access to ART services, particularly for patients at higher risk, and patients at risk for LTFU after ART initiation should be targeted through enhancing treatment counselling and improving patient tracing system at ART clinics.
Journal ArticleDOI
Does thyroid peroxidase provide an antigenic link between thyroid autoimmunity and breast cancer
Ilaria Muller,Ilaria Muller,Claudio Giani,Lei Zhang,Fiona Grennan-Jones,Emilio Fiore,V. Belardi,Veronica Rosellini,Niccola Funel,Daniela Campani,E. Giustarini,M. D. Lewis,Ameen Bakhsh,Manuela Roncella,M. Ghilli,Paolo Vitti,Colin M. Dayan,Marian Ludgate +17 more
TL;DR: TPO is weakly expressed in BC and other tissues; this could partly explain the high frequency and protective role of TPOAb in BC patients and further studies will investigate tissue specificity, function and immunogenicity of the novel TPO variants identified.
Journal ArticleDOI
Combining micro-RNA and protein sequencing to detect robust biomarkers for Graves’ disease and orbitopathy
Lei Zhang,Giulia Masetti,Giulia Masetti,Giuseppe Colucci,Mario Salvi,Danila Covelli,Anja Eckstein,Ulrike Kaiser,Mohd Shazli Draman,Ilaria Muller,Marian Ludgate,Luigi Lucini,Filippo Biscarini,Filippo Biscarini +13 more
TL;DR: Proteomic and miRNA analyses, combined with robust bioinformatics, identified circulating biomarkers applicable to diagnose Graves’ Disease, predict GO disease status and optimize patient management.
Journal ArticleDOI
Distributions and trends in sexual behaviors and HIV incidence among men who have sex with men in China.
TL;DR: Regular partnerships are the main contributor of new HIV cases among MSM in China, public health intervention strategies are required to increase condom usage and HIV testing rates among regular partners to curb the growing trend HIV incidence.
Journal ArticleDOI
Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus.
TL;DR: This work demonstrates that ethanol tolerance of K. marxianus can be improved by engineering its TATA-binding protein Spt15, which is able to bring differential expression of hundreds of genes that acted as an interconnected network for the phenotype of ethanol tolerance.