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Leif Bertilsson

Researcher at Karolinska University Hospital

Publications -  321
Citations -  24620

Leif Bertilsson is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Debrisoquine & Debrisoquin. The author has an hindex of 87, co-authored 321 publications receiving 23933 citations. Previous affiliations of Leif Bertilsson include Astra & University of Oulu.

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Journal ArticleDOI

Effect of terbinafine and voriconazole on the pharmacokinetics of the antidepressant venlafaxine.

Ville-Veikko Hynninen, +5 more
- 01 Feb 2008 - 
TL;DR: The most likely mechanism for the interaction between terbinafine and venlafaxine is the inhibition of CYP2D6‐mediated O‐demethylation of venl Lafaxine, whereas the minor effects of voriconazole are probably due to the inhibition.
Journal ArticleDOI

Factors influencing the metabolism of diazepam.

Leif Bertilsson, +2 more
- 01 Jan 1990 - 
TL;DR: Theabolism of diazepam and related benzodiazepines: factors influencing the interindividual variation in the kinetics and metabolism (environmental factors, genetic factors)
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Pronounced Differences in the Disposition of Clomipramine Between Japanese and Swedish Patients

Kazutaka Shimoda, +5 more
- 01 Oct 1999 - 
TL;DR: The aim of this study was to compare the disposition of the tricyclic antidepressant clomipramine in Japanese and Swedish patients receiving continuous treatment and to find out whether there is a true ethnic difference.
Journal ArticleDOI

Determination of isomeric acid dopamine metabolites in human cerebrospinal fluid by mass fragmentography.

Leif Bertilsson, +1 more
- 01 Oct 1973 - 
TL;DR: It was found that the concentration of iso-HVA was less than 2% of the HVA level in the investigated 12 CSF samples from patients with different diseases.
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Glucuronidation of amitriptyline in man in vivo.

Marja-Liisa Dahl-Puustinen, +2 more
- 01 Jul 1989 - 
TL;DR: The present study shows that direct glucuronidation is a minor metabolic pathway of AT in man in vivo both after single low doses and during continuous treatment with therapeutic doses.