L
Li Yang
Researcher at Chinese Academy of Sciences
Publications - 634
Citations - 30233
Li Yang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 63, co-authored 349 publications receiving 22474 citations. Previous affiliations of Li Yang include Tongji University & University of Connecticut Health Center.
Papers
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Journal ArticleDOI
Circular Intronic Long Noncoding RNAs
Yang Zhang,Xiao-Ou Zhang,Tian Chen,Jian-Feng Xiang,Qing-Fei Yin,Yu-Hang Xing,Shanshan Zhu,Li Yang,Ling-Ling Chen +8 more
TL;DR: A cis-regulatory role of noncoding intronic transcripts on their parent coding genes is suggested, which largely accumulates to its sites of transcription, associates with elongation Pol II machinery, and acts as a positive regulator of Pol II transcription.
Journal ArticleDOI
Complementary Sequence-Mediated Exon Circularization
TL;DR: It is demonstrated that exon circularization is dependent on flanking intronic complementary sequences in human introns and that alternative formation of inverted repeated Alu pairs can lead to alternative circularization, resulting in multiple circular RNA transcripts produced from a single gene.
Journal ArticleDOI
The developmental transcriptome of Drosophila melanogaster
Brenton R. Graveley,Angela N. Brooks,Joseph W. Carlson,Michael O. Duff,Jane M. Landolin,Li Yang,Carlo G. Artieri,Marijke J. van Baren,Nathan Boley,Benjamin W. Booth,James B. Brown,Lucy Cherbas,Carrie A. Davis,Alexander Dobin,Renhua Li,Wei Lin,John H. Malone,Nicolas R. Mattiuzzo,David Scott Miller,David Sturgill,Brian B. Tuch,Brian B. Tuch,Chris Zaleski,Dayu Zhang,Marco Blanchette,Marco Blanchette,Sandrine Dudoit,Brian D. Eads,Richard E. Green,Ann S. Hammonds,Lichun Jiang,Phil Kapranov,Laura Langton,Norbert Perrimon,Jeremy E. Sandler,Kenneth H. Wan,Aarron T. Willingham,Yu Zhang,Yi Zou,Justen Andrews,Peter J. Bickel,Steven E. Brenner,Michael R. Brent,Peter Cherbas,Thomas R. Gingeras,Thomas R. Gingeras,Roger A. Hoskins,Thomas C. Kaufman,Brian Oliver,Susan E. Celniker +49 more
TL;DR: 111,195 new elements are identified, including thousands of genes, coding and non-coding transcripts, exons, splicing and editing events and inferred protein isoforms that previously eluded discovery using established experimental, prediction and conservation-based approaches.
Journal ArticleDOI
Regulation of circRNA biogenesis
Ling-Ling Chen,Li Yang +1 more
TL;DR: Current understanding of the regulation of circRNA biogenesis is highlighted, including both the competition between splicing and back-splicing and the previously under-appreciated alternative circularization.
Journal ArticleDOI
The Biogenesis, Functions, and Challenges of Circular RNAs.
TL;DR: The recent progress on circRNA biogenesis and function is surveyed and technical obstacles in circRNA studies are discussed.