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M. E. de Vera

Researcher at University of Pittsburgh

Publications -  13
Citations -  1747

M. E. de Vera is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Transplantation & Liver transplantation. The author has an hindex of 11, co-authored 13 publications receiving 1534 citations. Previous affiliations of M. E. de Vera include Loma Linda University.

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Journal ArticleDOI

2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

Anthony J. Demetris, +76 more
TL;DR: New recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization are included.
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Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter.

TL;DR: The data demonstrate that the human NOS2 gene is transcriptionally regulated by cytokines and identify multiple cytokine-responsive regions in the 5' flanking region of thehuman NOS1 gene.
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Liver Transplantation Using Donation After Cardiac Death Donors: Long-Term Follow-Up from a Single Center

TL;DR: There was a lack of survival benefit in DCD livers utilized in patients with model for end‐stage liver disease (MELD) ≤30 or those not on organ‐perfusion support, as graft survival was significantly lower compared to DBD patients, however, DCD and DBD subjects transplanted with MELD >30 or on organ-perfusions support had similar graft survival, suggesting a potentially greater benefit of DCDLivers in critically ill patients.
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Survival of liver transplant patients coinfected with HIV and HCV is adversely impacted by recurrent hepatitis C.

TL;DR: Recurrent HCV in 18 patients was associated with eight deaths, including three from fibrosing cholestatic hepatitis, and of 15 patients treated with interferon‐α/ribavirin, six (40%) are HCV RNA negative, including four with sustained virological response.
Journal Article

A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis.

TL;DR: Rats injected with both LPS and IL-1ra showed decreased hepatic iNOS mRNA and plasma NO2- + NO3- compared with rats given LPS alone, indicating thatIL-1 beta plays a role in regulating iN OS expression within the liver in vivo during endotoxemia.