M
Marcus M. Unger
Researcher at Saarland University
Publications - 66
Citations - 3304
Marcus M. Unger is an academic researcher from Saarland University. The author has contributed to research in topics: Parkinson's disease & Ghrelin. The author has an hindex of 22, co-authored 62 publications receiving 2480 citations. Previous affiliations of Marcus M. Unger include University of Marburg & University of Hamburg.
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Journal ArticleDOI
Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls.
Marcus M. Unger,Jörg Spiegel,Klaus-Ulrich Dillmann,David Grundmann,Hannah Philippeit,Jan Bürmann,Klaus Faßbender,Andreas Schwiertz,Karl-Herbert Schäfer +8 more
TL;DR: This study confirms the recently reported association between PD and the abundance of certain gut microbiota and shows a reduction in fecal SCFA concentrations, which might, theoretically, induce alterations in the ENS and contribute to gastrointestinal dysmotility in PD.
Journal ArticleDOI
A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study.
Ronald B. Postuma,Isabelle Arnulf,Birgit Högl,Alex Iranzo,Tomoyuki Miyamoto,Yves Dauvilliers,Wolfgang H. Oertel,Yo-El Ju,Monica Puligheddu,Poul Jennum,Amélie Pelletier,Christina Wolfson,Smaranda Leu-Semenescu,Birgit Frauscher,Masayuki Miyamoto,Valérie Cochen De Cock,Marcus M. Unger,Karin Stiasny-Kolster,Maria Livia Fantini,Maria Livia Fantini,Jacques Montplaisir +20 more
TL;DR: The RBD1Q screening question is designed, a screening question for dream enactment with a simple yes/no response foriopathic rapid eye movement sleep behavior disorder.
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Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: A multicenter study
Ronald B. Postuma,Alex Iranzo,Birgit Högl,Isabelle Arnulf,Luigi Ferini-Strambi,Raffaele Manni,Tomoyuki Miyamoto,Wolfgang H. Oertel,Yves Dauvilliers,Yo-El Ju,Monica Puligheddu,Karel Sonka,Amélie Pelletier,Juan Santamaria,Birgit Frauscher,Smaranda Leu-Semenescu,Marco Zucconi,Michele Terzaghi,Masayuki Miyamoto,Marcus M. Unger,Bertrand Carlander,Maria Livia Fantini,Maria Livia Fantini,Jacques Montplaisir +23 more
TL;DR: To assess whether risk factors for Parkinson disease and dementia with Lewy bodies increase rate of defined neurodegenerative disease in idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), a large number of animals were sacrificed for research purposes.
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Rapid eye movement sleep behavior disorder: Devising controlled active treatment studies for symptomatic and neuroprotective therapy-a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group
Carlos H. Schenck,Jacques Montplaisir,Birgit Frauscher,Birgit Högl,Jean Gagnon,Ronald B. Postuma,Karel Sonka,P. Jennum,Markku Partinen,Isabelle Arnulf,V. Cochen De Cock,Yves Dauvilliers,Pierre-Hervé Luppi,Anna Heidbreder,Geert Mayer,Friederike Sixel-Döring,Claudia Trenkwalder,Marcus M. Unger,Marcus M. Unger,Peter Young,Yun Kwok Wing,Luigi Ferini-Strambi,Raffaele Ferri,Giuseppe Plazzi,Marco Zucconi,Y. Inoue,A. Iranzo,J. Santamaria,Claudio L. Bassetti,Jens Carsten Möller,B. F. Boeve,Yuan-Yang Lai,Milena Pavlova,Clifford B. Saper,P. Schmidt,Jerome M. Siegel,Carlos Singer,E. St. Louis,Aleksandar Videnovic,W. H. Oertel +39 more
TL;DR: The IRBD-SG provides an important platform for developing multinational collaborative studies on RBD such as on environmental risk factors for iRBD, and on controlled active treatment studies for symptomatic and neuroprotective therapy that emerged during the 2011 consensus conference in Marburg, Germany, as described in this report.
Journal ArticleDOI
Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease
Andreas Schwiertz,Jörg Spiegel,Ulrich Dillmann,David Grundmann,Jan Bürmann,Klaus Faßbender,Karl-Herbert Schäfer,Marcus M. Unger +7 more
TL;DR: The data indicate that calprotectin, alpha-1-antitrypsin and zonulin could be useful non-invasive markers in PD as well, and corroborate the hypothesis of an intestinal inflammation as contributing factor in the pathogenesis of PD.