M
Maria A. Suni
Researcher at Becton Dickinson
Publications - 18
Citations - 1952
Maria A. Suni is an academic researcher from Becton Dickinson. The author has contributed to research in topics: Antigen & T cell. The author has an hindex of 16, co-authored 18 publications receiving 1874 citations.
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Journal ArticleDOI
Use of overlapping peptide mixtures as antigens for cytokine flow cytometry
Holden T. Maecker,Holli S Dunn,Maria A. Suni,Elham Khatamzas,Elham Khatamzas,Christine J. Pitcher,Torsten Bunde,Natasha Persaud,Wendy L. Trigona,Tong-Ming Fu,Elizabeth Sinclair,Barry M. Bredt,Joseph M. McCune,Vernon C. Maino,Florian Kern,Louis J. Picker +15 more
TL;DR: Over overlapping 15 amino acid peptide mixes may facilitate the analysis of antigen-specific CD4+ and CD8+ T-cell responses by cytokine flow cytometry, using clinical specimens that include shipped blood or cryopreserved PBMC.
Journal ArticleDOI
Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry
TL;DR: A simplified procedural modification is described which enables the rapid detection of low frequency memory CD4+ and CD8+ T cells expressing cytokines in response to soluble antigen in whole blood.
Journal ArticleDOI
Standardization of cytokine flow cytometry assays
Holden T. Maecker,Aline Rinfret,Patricia D'Souza,Janice Darden,Eva Roig,Claire Landry,Peter Hayes,Josephine Birungi,Omu Anzala,Miguel Garcia,Alexandre Harari,Ian Frank,Ruth Baydo,Megan Baker,Jennifer Holbrook,Janet Ottinger,Laurie Lamoreaux,C. Lorrie Epling,Elizabeth Sinclair,Maria A. Suni,Kara Punt,Sandra A. Calarota,Sophia El-Bahi,Gailet Alter,Hazel Maila,Ellen G. Kuta,Josephine H. Cox,Clive M. Gray,Marcus Altfeld,Nolwenn Nougarede,Jean D. Boyer,Lynda G. Tussey,Timothy W. Tobery,Barry M. Bredt,Mario Roederer,Richard A. Koup,Vernon C. Maino,Kent J. Weinhold,Giuseppe Pantaleo,Jill Gilmour,Helen Horton,Rafick Pierre Sekaly +41 more
TL;DR: ICS assays can be performed by multiple laboratories using a common protocol with good inter-laboratory precision, which improves as the frequency of responding cells increases.
Journal ArticleDOI
Rapid flow cytometric method for measuring lymphocyte subset activation
TL;DR: A three-color flow cytometric method for the rapid analysis of individual T-cell subsets in whole blood responding to various provocative stimuli, including pokeweed mitogen, the comitogenic monoclonal antibodies (mAbs) CD2/CD2R, the superantigen staphylococcal enterotoxin B (SEB), and the specific antigen Candida albicans is described.
Journal ArticleDOI
VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC
Hailing Lu,Gregory N. Dietsch,Maura Matthews,Yi Yang,Smita Ghanekar,Margaret Inokuma,Maria A. Suni,Vernon C. Maino,Katherine E. Henderson,J. Jeffry Howbert,Mary L. Disis,Robert M. Hershberg +11 more
TL;DR: VTX-2337 is a novel small-molecule TLR8 agonist that activates monocytes, DCs, and NK cells and has the potential to augment the effectiveness of monoclonal antibody treatments where a polymorphism in FcγR3A limits clinical efficacy.