Martin Antonio

TL;DR: P phenotypic differences between MAF and Mycobacterium tuberculosis (MTB) among 692 tuberculosis patients infected with the two most common lineages within the MTB complex found in the Gambia, namely MAF West African type 2 and Euro-American MTB are identified.

TL;DR: Both TB-LAMP and GeneXpert showed high sensitivity and specificity regardless of age or strain of infection, and therefore would be most suitable as a screening test for new TB cases in peripheral health clinics.

TL;DR: Replacing PCV7 for PCV13 rapidly decreased prevalence of VT carriage among vaccinated Gambian infants and an indirect effect in mothers was not observed, suggesting vaccine-driven selection pressure may have been responsible for the increase of non-typable isolates.

TL;DR: In this article, the authors performed metagenomic sequencing of fifty chicken faecal samples from two breeds and analysed these, alongside all (n = 582) relevant publicly available chicken metagenomes, to cluster over 20 million non-redundant genes and to construct over 5,500 metagenome-assembled bacterial genomes.

TL;DR: Sensitivity to C3 deposition and opsonophagocytosis was associated with serotype-specific mortality of invasive pneumococcal disease, suggesting that the primary pathogens, such as serotypes 1 and 5, are more resistant to complement and require a higher concentration of capsule antibodies for opsonphagocytic killing than the opportunistic serotypes such as 6B and 23F, which are associated with a more severe disease outcome.