M
Martin Antonio
Researcher at University of London
Publications - 255
Citations - 15203
Martin Antonio is an academic researcher from University of London. The author has contributed to research in topics: Streptococcus pneumoniae & Population. The author has an hindex of 49, co-authored 235 publications receiving 11975 citations. Previous affiliations of Martin Antonio include University of Birmingham & Medical Research Council.
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Journal ArticleDOI
Immunogenic Mycobacterium africanum Strains Associated with Ongoing Transmission in The Gambia
Florian Gehre,Martin Antonio,Jacob Otu,Neneh Sallah,Oumie Secka,Tutty Faal,Patrick K. Owiafe,Jayne S. Sutherland,Ifedayo M. O. Adetifa,Martin O. C. Ota,Beate Kampmann,Tumani Corrah,Bouke C. de Jong +12 more
TL;DR: A positive correlation between strains with superior spreading capacity and their relative immunogenicity is found and is especially pronounced in M. africanum sublineage, characterized by spoligotype shared international type 181.
Journal ArticleDOI
Putative novel cps loci in a large global collection of pneumococci.
Andries J. van Tonder,Rebecca A. Gladstone,Stephanie W. Lo,Moon H. Nahm,Mignon du Plessis,Jennifer E. Cornick,Brenda Kwambana-Adams,Shabir A. Madhi,Paulina A. Hawkins,Rachel Benisty,Ron Dagan,Dean Everett,Martin Antonio,Keith P. Klugman,Anne von Gottberg,Robert F. Breiman,Robert F. Breiman,Lesley McGee,Stephen D. Bentley,Stephen D. Bentley +19 more
TL;DR: The large number and global distribution of GPS genomes provided an unprecedented opportunity to identify novel cps loci and consider their phylogenetic and geographical distribution and examples of each will undergo subsequent structural and immunological analysis.
Journal ArticleDOI
Community-acquired Invasive Bacterial Disease in Urban Gambia, 2005–2015: A Hospital-based Surveillance
Saffiatou Darboe,Uduak Okomo,Abdul-Khalie Muhammad,Buntung Ceesay,Mamadou Jallow,Effua Usuf,Sam Tweed,Edem N K Akpalu,Brenda Kwambana-Adams,Samuel Kariuki,Martin Antonio,Richard S. Bradbury,Karen Forrest,Thushan I de Silva,Bolarinde Lawal,Davis Nwakanma,Ousman Secka,Anna Roca +17 more
TL;DR: It is demonstrated that surveillance data on the predominant pathogens associated with invasive disease is necessary to inform vaccine priorities and appropriate management of patients and that antimicrobial resistance to common antibiotics was low.
Journal ArticleDOI
High genotypic diversity among rotavirus strains infecting Gambian children.
Brenda Kwambana,Usman N. Ikumapayi,Neneh Sallah,Michel M. Dione,Sheikh Jarju,Sandra Panchalingham,James Jafali,Modou Lamin,Modupeh Betts,Mitchell Adeyemi,Adebayo Akinsola,Ousman Bittaye,Momodou Jasseh,Karen L. Kotloff,Myron M. Levine,James P. Nataro,Tumani Corrah,Mostafa A. R. Hossain,Debasish Saha,Martin Antonio +19 more
TL;DR: The wide diversity of genotypes circulating in The Gambia implies the need for vigilant effectiveness surveillance following the implementation of RotaTeq in August 2013 and provides important baseline data for the genotype circulating before vaccine implementation.
Journal ArticleDOI
Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension.
Boatema Ofori-Anyinam,Abi Janet Riley,Tijan Jobarteh,Ensa Gitteh,Binta Sarr,Tutty Isatou Faal-Jawara,Leen Rigouts,Madikay Senghore,Aderemi Kehinde,Nneka Onyejepu,Martin Antonio,Bouke C. de Jong,Florian Gehre,Conor J. Meehan,Conor J. Meehan +14 more
TL;DR: Differences between MAF and MTB lineages are shown that may have contributed to the MAF clinical and growth phenotype and indicate potential adaptation of MAF lineages to a distinct ecological niche, which it is suggested includes areas characterized by low oxygen tension.