M
Martin Zwahlen
Researcher at Royal Institute of Technology
Publications - 19
Citations - 17266
Martin Zwahlen is an academic researcher from Royal Institute of Technology. The author has contributed to research in topics: Gene & Human Protein Atlas. The author has an hindex of 9, co-authored 13 publications receiving 12194 citations.
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Journal ArticleDOI
Tissue-based map of the human proteome
Mathias Uhlén,Mathias Uhlén,Linn Fagerberg,Björn M. Hallström,Cecilia Lindskog,Per Oksvold,Adil Mardinoglu,Åsa Sivertsson,Caroline Kampf,Evelina Sjöstedt,Evelina Sjöstedt,Anna Asplund,IngMarie Olsson,Karolina Edlund,Emma Lundberg,Sanjay Navani,Cristina Al-Khalili Szigyarto,Jacob Odeberg,Dijana Djureinovic,Jenny Ottosson Takanen,Sophia Hober,Tove Alm,Per-Henrik Edqvist,Holger Berling,Hanna Tegel,Jan Mulder,Johan Rockberg,Peter Nilsson,Jochen M. Schwenk,Marica Hamsten,Kalle von Feilitzen,Mattias Forsberg,Lukas Persson,Fredric Johansson,Martin Zwahlen,Gunnar von Heijne,Jens Nielsen,Jens Nielsen,Fredrik Pontén +38 more
TL;DR: In this paper, a map of the human tissue proteome based on an integrated omics approach that involves quantitative transcriptomics at the tissue and organ level, combined with tissue microarray-based immunohistochemistry, to achieve spatial localization of proteins down to the single-cell level.
Journal ArticleDOI
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
Linn Fagerberg,Björn M. Hallström,Per Oksvold,Caroline Kampf,Dijana Djureinovic,Jacob Odeberg,Masato Habuka,Simin Tahmasebpoor,Angelika Danielsson,Karolina Edlund,Anna Asplund,Evelina Sjöstedt,Emma Lundberg,Cristina Al-Khalili Szigyarto,Marie Skogs,Jenny Ottosson Takanen,Holger Berling,Hanna Tegel,Jan Mulder,Peter Nilsson,Jochen M. Schwenk,Cecilia Lindskog,Frida Danielsson,Adil Mardinoglu,Åsa Sivertsson,Kalle von Feilitzen,Mattias Forsberg,Martin Zwahlen,IngMarie Olsson,Sanjay Navani,Mikael Huss,Jens Nielsen,Jens Nielsen,Fredrik Pontén,Mathias Uhlén +34 more
TL;DR: A quantitative transcriptomics analysis (RNA-Seq) is used to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues.
Journal ArticleDOI
Towards a knowledge-based Human Protein Atlas
Mathias Uhlén,Per Oksvold,Linn Fagerberg,Emma Lundberg,Kalle Jonasson,Mattias Forsberg,Martin Zwahlen,Caroline Kampf,Kenneth Wester,Sophia Hober,Henrik Wernérus,Lisa Björling,Fredrik Pontén +12 more
TL;DR: The analysis here suggests that state stem cell funding programs are sufficiently large and established that simply ending the programs, at least in the absence of substantial investment in the field by other funding sources, could have deleterious effects.
Journal ArticleDOI
A subcellular map of the human proteome
Peter Thul,Lovisa Åkesson,Mikaela Wiking,Diana Mahdessian,Aikaterini Geladaki,Hammou Ait Blal,Tove Alm,Anna Asplund,Lars Björk,Lisa M. Breckels,Anna Bäckström,Frida Danielsson,Linn Fagerberg,Jenny Fall,Laurent Gatto,Christian Gnann,Sophia Hober,Martin Hjelmare,Fredric Johansson,Sunjae Lee,Cecilia Lindskog,Jan Mulder,Claire M. Mulvey,Peter Nilsson,Per Oksvold,Johan Rockberg,Rutger Schutten,Jochen M. Schwenk,Åsa Sivertsson,Evelina Sjöstedt,Marie Skogs,Charlotte Stadler,Devin P. Sullivan,Hanna Tegel,Casper F. Winsnes,Cheng Zhang,Martin Zwahlen,Adil Mardinoglu,Fredrik Pontén,Kalle von Feilitzen,Kathryn S. Lilley,Mathias Uhlén,Emma Lundberg +42 more
TL;DR: A subcellular map of the human proteome is presented to facilitate functional exploration of individual proteins and their role in human biology and disease and integrated into existing network models of protein-protein interactions for increased accuracy.
Journal ArticleDOI
A single-cell type transcriptomics map of human tissues.
Max J. Karlsson,Cheng Zhang,Loren Méar,Wen Zhong,Andreas Digre,Borbala Katona,Evelina Sjöstedt,Lynn M. Butler,Jacob Odeberg,Philip Dusart,Fredrik Edfors,Per Oksvold,Kalle von Feilitzen,Martin Zwahlen,Muhammad Arif,Ozlem Altay,Xiangyu Li,Mehmet Ozcan,Adil Mardinoglu,Linn Fagerberg,Jan Mulder,Yonglun Luo,Fredrik Pontén,Mathias Uhlén,Mathias Uhlén,Cecilia Lindskog +25 more
TL;DR: In this article, the authors combined single-cell transcriptomics analysis with spatial antibody-based protein profiling to create a high-resolution singlecell type map of human tissues, which was used to explore the expression of human protein-coding genes in 192 individual cell type clusters.