Mary Pat Jones

TL;DR: The findings suggest that HRPT2 is a tumor-suppressor gene, the inactivation of which is directly involved in predisposition to HPT–JT and in development of some sporadic parathyroid tumors.

TL;DR: Analysis of 33 additional multiplex families with CMM from several continents provided further evidence for linkage to the 1p22 region, again strongest in families with the earliest mean age at diagnosis, providing significant evidence of a novel susceptibility gene for CMM located within chromosome band 1p 22.

TL;DR: This work has identified several putative prostate cancer candidate genes located on chromosomes 1, 20, and X and identified RNASEL, MSR1, and ELAC2, which appear to explain only a small proportion of hereditary prostate cancer cases.

TL;DR: It is found that small intestinal carcinoids can occur as an inherited autosomal-dominant disease and relatives of patients with familial carcinoids should be screened to detect curable early stage disease.

TL;DR: Fine mapping studies to facilitate identification of prostate cancer susceptibility genes in these linked regions are warranted.