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Wilma Bergman
Researcher at Leiden University
Publications - 120
Citations - 8301
Wilma Bergman is an academic researcher from Leiden University. The author has contributed to research in topics: CDKN2A & Melanoma. The author has an hindex of 40, co-authored 120 publications receiving 7851 citations. Previous affiliations of Wilma Bergman include University of Sydney & Leiden University Medical Center.
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Journal ArticleDOI
Analysis of the p16 gene (CDKN2) as a candidate· for the chromosome 9p melanoma susceptibility locus
Alexander Kamb,Donna M Shattuck-Eidens,Rosalind A. Eeles,Rosalind A. Eeles,Qingyun Liu,Nelleke A. Gruis,Nelleke A. Gruis,Wei Ding,Charles E. Hussey,Thanh Tran,Yoshio Miki,Jane Weaver-Feldhaus,Melody McClure,Joanne F. Aitken,David E. Anderson,Wilma Bergman,Rune R. Frants,David E. Goldgar,Adèle C. Green,Robert MacLennan,Nicholas G. Martin,Laurence Meyer,Laurence Meyer,P. Youl,John J. Zone,Mark H. Skolnick,Mark H. Skolnick,Lisa A. Cannon-Albright +27 more
TL;DR: A locus for familial melanoma, MLM, has been mapped within the same interval on chromosome 9p21 as the gene for a putative cell cycle regulator, p16INK4 (CDKN2) MTS1, suggesting that CDKN2 is a good candidate for MLM.
Journal ArticleDOI
Geographical Variation in the Penetrance of CDKN2A Mutations for Melanoma
D. Timothy Bishop,Florence Demenais,Alisa M. Goldstein,Wilma Bergman,Julia A. Newton Bishop,Brigitte Bressac-de Paillerets,Agnès Chompret,Paola Ghiorzo,Nelleke A. Gruis,Johan Hansson,Mark Harland,Nicholas K. Hayward,Elizabeth A. Holland,Graham J. Mann,Michela Mantelli,Derek J. Nancarrow,Anton Platz,Margaret A. Tucker +17 more
TL;DR: This study indicates that the penetrance of CDKN2A mutation penetrance varies with melanoma population incidence rates, and suggests that the same factors that affect population incidence of melanoma may also mediate CD KN2A penetrance.
Journal ArticleDOI
Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color.
C. Kennedy,Jeanet A.C. ter Huurne,Marjo J.P. Berkhout,Nelleke A. Gruis,Maarten T. Bastiaens,Wilma Bergman,Rein Willemze,Jan Nico Bouwes Bavinck +7 more
TL;DR: In this article, the authors evaluated the relationship of melanocortin 1 receptor gene variants, fair skin, red hair and the development of melanoma in 123 patients with cutaneous melanoma and 385 control subjects.
Journal ArticleDOI
High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL
Alisa M. Goldstein,May Chan,Mark Harland,Elizabeth M. Gillanders,Nicholas K. Hayward,Marie-Françoise Avril,Esther Azizi,Giovanna Bianchi-Scarrà,D. Timothy Bishop,Brigitte Bressac-de Paillerets,William Bruno,Donato Calista,Lisa A. Cannon Albright,Florence Demenais,David E. Elder,Paola Ghiorzo,Nelleke A. Gruis,Johan Hansson,David W. Hogg,Elizabeth A. Holland,Peter A. Kanetsky,Richard F. Kefford,Maria Teresa Landi,Julie Lang,Sancy A. Leachman,Rona M. MacKie,Veronica Magnusson,Graham J. Mann,Kristin B. Niendorf,Julia A. Newton Bishop,Jane M. Palmer,Susana Puig,Joan Anton Puig-Butille,Femke A. de Snoo,Mitchell S. Stark,Hensin Tsao,Margaret A. Tucker,Linda Whitaker,Emanuel Yakobson,Joseph Malvehy,Celia Badenas,R. Cervera,Francisco Cuellar,Francisco Cuellar,Rosa M. Martí,Joan Brunet-Vidal,Guang Yang,Nicholas G. Martin,David C. Whiteman,Adèle C. Green,Joanne F. Aitken,Paola Minghetti,Michela Mantelli,Lorenza Pastorino,Sabina Nasti,Sara Gargiulo,Sara Gliori,Sushila Mistry,Juliette Randerson-Moor,Wilma Bergman,Jeanet A.C. ter Huurne,Clasine van der Drift,Leny van Mourik,Coby Out-Luiting,Frans A. van Nieuwpoort,Valérie Chaudru,Agnès Chompret,Caroline Kanengiesser,J. L. Michel,Florent Grange,B. Sassolas,Jean -Marc Limacher,D. Couillet,F. Truchetet,J. P. Cesarini,F. Boitier,Jacqueline Chevrant-Breton,Christine Lasset,Michel Longy,Pascal Joly,Nicole Basset-Seguin,T. Lesimple,Catherine Dugast,Arupa Ganguly,Michael Ming,Patricia Van Belle,Anton Platz,Suzanne Egyhazi,Rainer Tuominen,Diana Linden,Helen Schmid,Alon Scope,Felix Pavlotsky,Eitan Friedman,Mark J. Eliason,Christian Ingvar,Åke Borg,Johan Westerdahl,Anna Måsbäck,Håkan Olsson +99 more
TL;DR: This GenoMEL study provides the most extensive characterization of mutations in high-risk melanoma susceptibility genes in families with three or more melanoma patients yet available and there was little evidence for an association between CDKN2A mutations and NST, but there was a marginally significant association between NST and ARF.
Journal ArticleDOI
Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma‐prone families from three continents
Alisa M. Goldstein,May Chan,Mark Harland,Nicholas K. Hayward,Florence Demenais,D. Timothy Bishop,Esther Azizi,Wilma Bergman,Giovanna Bianchi-Scarrà,William Bruno,Donato Calista,Lisa A. Cannon Albright,Valérie Chaudru,Agnès Chompret,Francisco Cuellar,David E. Elder,Paola Ghiorzo,Elizabeth M. Gillanders,Nelleke A. Gruis,Johan Hansson,David W. Hogg,Elizabeth A. Holland,Peter A. Kanetsky,Richard F. Kefford,Maria Teresa Landi,Julie Lang,Sancy A. Leachman,Rona M. MacKie,Veronica Magnusson,Graham J. Mann,Julia A. Newton Bishop,Jane M. Palmer,Susana Puig,Joan Anton Puig-Butille,Mitchell S. Stark,Hensin Tsao,Margaret A. Tucker,Linda Whitaker,Emanuel Yakobson +38 more
TL;DR: The variation in CDKN2A mutations for the four features across continents is consistent with the lower melanoma incidence rates in Europe and higher rates of sporadic melanoma in Australia, which reflects the divergent spectrum of mutations in families from Australia versus those from North America and Europe.