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Mathew A. Beale

Researcher at Wellcome Trust Sanger Institute

Publications -  46
Citations -  1863

Mathew A. Beale is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Population & Biology. The author has an hindex of 13, co-authored 37 publications receiving 994 citations. Previous affiliations of Mathew A. Beale include St George's, University of London & University College London.

Papers
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Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.

Katherine A Twohig, +607 more
TL;DR: In this paper, the authors compared the severity of the delta variant compared with the alpha variant by determining the relative risk of hospital attendance outcomes and found that outbreaks of the Delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variants.
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Clinical and biological insights from viral genome sequencing.

TL;DR: It is suggested that WGS of viruses in a clinical setting will become increasingly important for patient care.
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Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

TL;DR: In this paper, a whole-genome sequencing (WGS) was performed for high-resolution single-nucleotide polymorphism (SNP) analysis of 24 A. fumigatus isolates, including azole-resistant and susceptible clinical and environmental strains obtained from India, the Netherlands, and the United Kingdom, in order to assess the utility of WGS for characterizing the alleles causing resistance.
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Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis

TL;DR: Characterization of fungal-specific pathways that drive clinical manifestation provide potential targets for the development of therapeutics and the management of Cryptococcal meningitis.
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Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors

TL;DR: Reports of persistent HEV infection with serious disease sequelae indicate that transfusion transmitted HEV is not a trivial disease in immunosuppressed patients.