M
Matilde Todaro
Researcher at University of Palermo
Publications - 163
Citations - 19136
Matilde Todaro is an academic researcher from University of Palermo. The author has contributed to research in topics: Cancer stem cell & Stem cell. The author has an hindex of 55, co-authored 154 publications receiving 17289 citations. Previous affiliations of Matilde Todaro include University of Rome Tor Vergata.
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Journal ArticleDOI
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
Richard Anney,Andreja Avbersek,David J. Balding,Larry Baum,Felicitas Becker,Samuel F. Berkovic,Jonathan P. Bradfield,Lawrence C. Brody,Russell J. Buono,Claudia B. Catarino,Gianpiero L. Cavalleri,Stacey S. Cherny,Krishna Chinthapalli,Alison J. Coffey,Alastair Compston,Patrick Cossette,G-J. de Haan,P. De Jonghe,C. G. F. de Kovel,Norman Delanty,Chantal Depondt,Dennis J. Dlugos,Colin P. Doherty,Christian E. Elger,Thomas N. Ferraro,Martha Feucht,Andre Franke,Jacqueline A. French,Verena Gaus,David Goldstein,Hongsheng Gui,Youling Guo,Hakon Hakonarson,K. Hallman,Erin L. Heinzen,Ingo Helbig,H. Hjalgrim,Matilda R. Jackson,Jenny Jamnadas-Khoda,D. Janz,Marvin Johnson,Reetta Kälviäinen,A-M. Kantanen,Dalia Kasperaviciute,D. Kasteleijn-Nolst Trenite,Bobby P. C. Koeleman,Wolfram S. Kunz,Patrick Kwan,Y. Lung Lau,A E Lehesjoki,Holger Lerche,Costin Leu,Wolfgang Lieb,Dick Lindhout,Warren D. Lo,Daniel H. Lowenstein,Alberto Malovini,Anthony G Marson,Mark McCormack,J. M. Mills,M. Moerzinger,Rikke S. Møller,Anne M. Molloy,Hiltrud Muhle,Mark R Newton,P-W. Ng,Markus M. Nöthen,Peter Nürnberg,Terence J. O'Brien,Karen Oliver,A. Palotie,Faith Pangilinan,Katharina Pernhorst,Slavé Petrovski,Michael Privitera,Rodney A. Radtke,Philipp S. Reif,Felix Rosenow,A-K. Ruppert,Thomas Sander,Theresa Scattergood,Steven C. Schachter,Christoph J. Schankin,Ingrid E. Scheffer,Bettina Schmitz,Susanne Schoch,PC Sham,SM Sisodiya,David F. Smith,Philip E. M. Smith,Doug Speed,Michael R. Sperling,Michael Steffens,U. Stephanie,Pasquale Striano,H. Stroink,Rainer Surges,K. M. Tan,GN Thomas,Matilde Todaro,Anna Tostevin,Rossana Tozzi,Holger Trucks,Frank Visscher,S. von Spiczak,Nicole M. Walley,Yvonne G. Weber,Zhi Wei,Christopher D. Whelan,W. Yang,Federico Zara,Fritz Zimprich +111 more
TL;DR: This meta-analysis describes a new locus not previously implicated in epilepsy and provides further evidence about the genetic architecture of these disorders, with the ultimate aim of assisting in disease classification and prognosis.
Journal ArticleDOI
Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
Ylenia Lombardo,Alessandro Scopelliti,Patrizia Cammareri,Matilde Todaro,Flora Iovino,Lucia Ricci Vitiani,Gaspare Gulotta,Francesco Dieli,Ruggero De Maria,Giorgio Stassi +9 more
TL;DR: BMP4 promotes terminal differentiation, apoptosis, and chemosensitization of CRC-SCs in tumors that do not have simultaneous mutations in Smad4 and constitutive activation of PI3K.
Journal ArticleDOI
Tumorigenic and metastatic activity of human thyroid cancer stem cells.
Matilde Todaro,Flora Iovino,Vincenzo Eterno,Patrizia Cammareri,Guido Gambara,Virginia Espina,Gaspare Gulotta,Francesco Dieli,Silvia Giordano,Ruggero De Maria,Giorgio Stassi +10 more
TL;DR: The identification of tumorigenic and metastagenic thyroid cancer cells may provide unprecedented preclinical tools for development and preclinical validation of novel targeted therapies.
Journal ArticleDOI
Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4.
Matilde Todaro,Ylenia Lombardo,Maria Giovanna Francipane,M. Perez Alea,Patrizia Cammareri,Flora Iovino,A. Di Stefano,C Di Bernardo,Antonino Agrusa,Gerolama Condorelli,Henning Walczak,Giorgio Stassi +11 more
TL;DR: Results indicate that inhibition of IL-4/IL-4R signaling may serve as a novel treatment for epithelial cancers and act as an autocrine survival factor in epithelial cells.
Journal ArticleDOI
Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
Domenico Ciavardelli,Cosmo Rossi,Daniela Barcaroli,Silvia Volpe,Ada Consalvo,Mirco Zucchelli,A De Cola,Emanuela Scavo,R. Carollo,Daniela D'Agostino,Federica Forlì,Simona D'Aguanno,Matilde Todaro,Giorgio Stassi,C Di Ilio,De Laurenzi,Andrea Urbani +16 more
TL;DR: It is suggested that inhibition of glycolysis may be a potentially effective strategy to target BCSCs, and functional validation of proteomic and metabolic data provide evidences for increased activities of key enzymes of anaerobic glucose fate in cancer stem cells as well as different redox status.