M
Mehmet Toner
Researcher at Harvard University
Publications - 572
Citations - 60830
Mehmet Toner is an academic researcher from Harvard University. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 113, co-authored 550 publications receiving 54827 citations. Previous affiliations of Mehmet Toner include University of New Mexico & University of Notre Dame.
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Patent
Isolating and analyzing rare brain-derived cells and particles
TL;DR: In this article, systems and methods for isolating, detecting, and/or analyzing brain-derived cells or particles in the blood circulation of human and animal subjects are described. But none of these methods are suitable for the detection of brain lesions.
Patent
Co-culture de cellules dans une configuration micromodelisee
TL;DR: In this paper, a procedure for production of co-cultures of cellules is described, in which cellules are configures dans un micromodele sur un substrat de facon that the modulation de l'etendue des contacts cellules-cellules heterotypiques puisse andre utilisee for moduler des fonctions metaboliques and/ou synthetiques des cellules.
Journal ArticleDOI
Abstract CT073: Efficacy of novel oral SERD elacestrant in fulvestrant-refractory hormone receptor-positive (HR+) breast cancer: a translational investigation
Taronish D. Dubash,Aditya Bardia,Brian Chirn,Brittany A. Reeves,Joseph A. LiCausi,Risa Burr,Ben S. Wittner,Sumit Rai,Hitisha K. Patel,Teeru Bihani,Heike Arlt,François-Clément Bidard,Virginia G. Kaklamani,Philippe Aftimos,Javier Cortes,Simona Scartoni,Monica Binaschi,Nassir Habboubi,A. John Iafrate,Mehmet Toner,Daniel A. Haber,Shyamala Maheswaran +21 more
TL;DR: In this article , a new generation oral selective estrogen receptor degrader (SERD) and antagonist, elacestrant, has demonstrated efficacy in a subset of women with advanced HR+ breast cancer, but there are few patient-derived models to characterize its effect in advanced cancers with diverse treatment histories and acquired mutations.
Microfluidic synthesis of squishy bio-mimetic particles with tunable deformability
TL;DR: In this article, a method based on photopolymerization in microfluidic devices was proposed for the synthesis of polymeric hydrogel microparticles with anisotropic shape and tunable flexibility.
Proceedings ArticleDOI
Microfabrication of basal lamina analogs with complex topographic features
TL;DR: In this article, a microfabrication approach was used to produce novel analogs of the basal lamina with complex topographic features, which can help to elucidate the influence of topography on epithelial cell proliferation and differentiation and should have applications in the tissue engineering of skin equivalents.