Mehmet Toner

TL;DR: In order to examine their potential for use in a bioartificial liver, hepatocytes maintained in a collagen sandwich configuration were cultured for 9 days in heparinized rat plasma and exhibited a progressive accumulation of cytoplasmic lipid droplets which proved to be mainly TG.

TL;DR: It is shown for the first time that blood settling can be prevented using polymers and has implications in diagnostics.

TL;DR: The presence and extent of intratumoral heterogeneity as revealed through the study of CTCs have important clinical implications for understanding and predicting the development of treatment resistance in a variety of solid tumors and for formulating appropriate therapeutic strategies in the effective treatment of cancer.

TL;DR: A microfluidic chip that continuously isolates untouched CTC clusters from large volumes of minimally (or undiluted) whole blood will enable cluster-specific diagnostics and speed the generation of patient-specific CTC cluster lines.

TL;DR: In this paper, a preservation method for biological material having cell membranes is described, which includes reversibly porating the cell membranes, loading a bio-protective agent having bio-preservation properties to a predetermined intracellular concentration, preparing the bio-protect agent loaded biological material for storage, storing the biological material, recovering the stored biological material from storage, and reversing the cell membrane poration.