M
Mehmet Toner
Researcher at Harvard University
Publications - 572
Citations - 60830
Mehmet Toner is an academic researcher from Harvard University. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 113, co-authored 550 publications receiving 54827 citations. Previous affiliations of Mehmet Toner include University of New Mexico & University of Notre Dame.
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Journal ArticleDOI
Cryomicroscopic analysis of intracellular ice formation during freezing of mouse oocytes without cryoadditives
TL;DR: In undercooling experiments, IIF was not observed until approximately -20 degrees C (at which temperature the whole suspension was frozen spontaneously), suggesting the involvement of the external ice in the initiation of IIF between approximately -5 and -31 degrees C during freezing of oocytes.
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Cryopreservation of Isolated Primary Rat Hepatocytes: Enhanced Survival and Long-term Hepatospecific Function
Meindert N. Sosef,John M. Baust,Keishi Sugimachi,Alex Fowler,Ronald G. Tompkins,Mehmet Toner +5 more
TL;DR: This study demonstrates that isolated rat hepatocytes cryopreserved using HTS showed high viability, long-term hepatospecific function, and response to cytokine challenge, and may represent an important step forward to the utilization of cryopReserved isolated hepatocytes in bioartificial liver devices.
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Cell–cell interaction modulates neuroectodermal specification of embryonic stem cells
Biju Parekkadan,Yevgeny Berdichevsky,Daniel Irimia,Daniel Irimia,Avrum Leeder,Gabriel M. Yarmush,Mehmet Toner,Mehmet Toner,Mehmet Toner,John B. Levine,John B. Levine,Martin L. Yarmush,Martin L. Yarmush,Martin L. Yarmush +13 more
TL;DR: This study demonstrates the integration of microscale culture techniques to explore the biology of ES cells and gain insight into relevant developmental processes otherwise undefined due to bulk culture methods.
Hepatic tissue engineering for adjunct and temporary liver support
Francois Berthiaume,Arno W. Tilles,Mehmet Toner,Martin L. Yarmush,Christina Chan,Christina Chan +5 more
TL;DR: This review describes, from an engineering perspective, the progress and remaining challenges that must be resolved in order to develop the next generation of implantable and extracorporeal devices for adjunct or temporary liver assist.
Journal ArticleDOI
Cryobiology of non-human primate oocytes
TL;DR: The cumulative fraction of oocytes with intracellular ice as a function of the cooling rate was predicted, and it was shown to correlate reasonably with experimental observations.