M
Mehmet Toner
Researcher at Harvard University
Publications - 572
Citations - 60830
Mehmet Toner is an academic researcher from Harvard University. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 113, co-authored 550 publications receiving 54827 citations. Previous affiliations of Mehmet Toner include University of New Mexico & University of Notre Dame.
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Nonmetabolizable Glucose Compounds Impart Cryotolerance to Primary Rat Hepatocytes
TL;DR: This is the first study to demonstrate the use of the non-metabolizable glucose derivative 3OMG in hepatocyte cryopreservation and maintained long-term hepatospecific functions, including synthesis, metabolism, and detoxification.
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Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime.
TL;DR: A robust, integrated poly(dimethylsiloxane) microchip interface for ESI-MS is reported using simple and widely accessible microfabrication procedures and stable cone-jet mode electrospray could be established over a far broader range of flow rates and applied potentials using the microchip emitters.
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Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells
Nilay Chakraborty,Michael A. Menze,Heidi Elmoazzen,Halong Vu,Martin L. Yarmush,Martin L. Yarmush,Steven C. Hand,Mehmet Toner +7 more
TL;DR: The beneficial effect of intracellular trehalose for imparting tolerance to partial desiccation is demonstrated and the potential of using a high-capacity TRET1 from the African chironomid Polypedilum vanderplanki to introducetrehalose into the cytoplasm of mammalian cells is explored.
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Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma.
Junji Washizu,Christina Chan,Francois Berthiaume,Ronald G. Tompkins,Mehmet Toner,Martin L. Yarmush +5 more
TL;DR: The results of this study indicate that hormone plus amino acid supplementation help to restore function in hepatocytes exposed to plasma.
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Antibody-functionalized fluid-permeable surfaces for rolling cell capture at high flow rates.
TL;DR: It is shown that a porous, fluid-permeable surface functionalized with cell-specific antibodies promotes efficient and selective cell capture in vitro and enables highly effective cell capture at flow rates more than an order of magnitude larger than those provided by existing devices with solid surfaces.