M
Mehmet Toner
Researcher at Harvard University
Publications - 572
Citations - 60830
Mehmet Toner is an academic researcher from Harvard University. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 113, co-authored 550 publications receiving 54827 citations. Previous affiliations of Mehmet Toner include University of New Mexico & University of Notre Dame.
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Journal ArticleDOI
Reversible permeabilization of plasma membranes with an engineered switchable pore.
TL;DR: It is demonstrated that the dose-dependent permeabilization of fibroblasts by pores designed to be blocked and unblocked by the addition and removal of μM concentrations of Zn2+.
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A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings.
Xuanhong Cheng,Daniel Irimia,Meredith Dixon,Joshua C. Ziperstein,Utkan Demirci,Lee Zamir,Ronald G. Tompkins,Mehmet Toner,William Rodriguez +8 more
TL;DR: A simple, label-free, and cost-effective CD4 cell counting device using microfluidic technology that can serve as a functional cartridge for fast, accurate, affordable, and simple CD 4 cell counting in resource-limited settings is designed.
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Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes.
P. Stefanovich,Robert M. Ezzell,S.J. Sheehan,Ronald G. Tompkins,Martin L. Yarmush,Mehmet Toner +5 more
TL;DR: The effects of hypothermia on long-term function and cytoskeletal organization of hepatocytes cultured in the collagen sandwich configuration, which maintains the expression of liver-specific functions for several weeks are characterized.
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Late embryogenesis abundant proteins protect human hepatoma cells during acute desiccation
TL;DR: LEA proteins dramatically enhance desiccation tolerance in mammalian cells and offer the opportunity for engineering biostability in the dried state.
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Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes.
TL;DR: The results of this study demonstrate the importance of oxygen during the initial stages of attachment and spreading of hepatocytes, and it has important implications in the design of hepatocyte‐based bioartificial liver devices.