M
Mehmet Toner
Researcher at Harvard University
Publications - 572
Citations - 60830
Mehmet Toner is an academic researcher from Harvard University. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 113, co-authored 550 publications receiving 54827 citations. Previous affiliations of Mehmet Toner include University of New Mexico & University of Notre Dame.
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Journal ArticleDOI
Changes in membrane integrity, cytoskeletal structure, and developmental potential of murine oocytes after vitrification in ethylene glycol.
TL;DR: Results indicate that EG is an effective CPA for mouse oocyte vitrification protocols without any observed compromise in morphology and developmental functions.
Journal ArticleDOI
Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics.
Xuanhong Cheng,Amit K. Gupta,Chihchen Chen,Ronald G. Tompkins,William Rodriguez,Mehmet Toner +5 more
TL;DR: An improved design of a two-stage microfluidic device to deplete monocytes from whole blood, followed by CD4+ T cell capture is reported, and microchip CD4 counts comparable to flow cytometry results in the full clinically relevant range are obtained.
Journal ArticleDOI
Overview of the Alliance for Cellular Signaling.
Alfred G. Gilman,Melvin I. Simon,Henry R. Bourne,Bruce A. Harris,Rochelle Long,Elliott M. Ross,James T. Stull,Ronald Taussig,Adam P. Arkin,Melanie H. Cobb,Jason G. Cyster,Peter N. Devreotes,James E. Ferrell,David A. Fruman,Michael R. Gold,Arthur Weiss,Michael J. Berridge,Lewis C. Cantley,William A. Catterall,Shaun R. Coughlin,Eric N. Olson,Temple F. Smith,Joan S. Brugge,David Botstein,Jack E. Dixon,Tony Hunter,Robert J. Lefkowitz,Anthony J. Pawson,Paul W. Sternberg,Harold E. Varmus,Shankar Subramaniam,Robert S. Sinkovits,Joshua Li,Dennis Mock,Yuhong Ning,Brian Saunders,Paul C. Sternweis,Donald W. Hilgemann,Richard H. Scheuermann,Dianne L. DeCamp,Robert C. Hsueh,Keng Mean Lin,Yan Ni,William E. Seaman,Paul C. Simpson,Timothy D. O'Connell,Tamara I. A. Roach,Sangdun Choi,Pamela Eversole-Cire,Iain D. C. Fraser,Marc C. Mumby,Yingming Zhao,Deirdre L. Brekken,Hongjun Shu,Tobias Meyer,Grischa Chandy,Won Do Heo,Jen Liou,Nancy A. O'Rourke,Mary Verghese,Susanne M. Mumby,Heping Han,H. Alex Brown,Jeffrey Forrester,Pavlina T. Ivanova,Stephen B. Milne,Patrick J. Casey,T. Kendall Harden,John Doyle,Martha L. Gray,Stephen W. Michnick,Martin A. Schmidt,Mehmet Toner,Roger Y. Tsien,Madhusudan Natarajan,Rama Ranganathan,Gilberto R. Sambrano +76 more
TL;DR: The Alliance for Cellular Signaling will study intensively in two cells — B lymphocytes (the cells of the immune system) and cardiac myocytes — to facilitate quantitative modelling.
Journal ArticleDOI
Deformability of Tumor Cells versus Blood Cells.
Josephine Shaw Bagnall,Sangwon Byun,Sangwon Byun,Shahinoor Begum,David T. Miyamoto,Vivian C. Hecht,Shyamala Maheswaran,Shannon L. Stott,Mehmet Toner,Richard O. Hynes,Scott R. Manalis +10 more
TL;DR: It is demonstrated that deformability changes in tumor cells that have undergone phenotypic shifts are small compared to differences between tumor cell lines and blood cells, and a limited study of metastatic prostate cancer patients provides evidence that some CTCs may be more mechanically similar to blood cells than to typical tumor cell Lines.
Journal ArticleDOI
Hepatic tissue engineering for adjunct and temporary liver support: critical technologies.
Christina Chan,Christina Chan,Francois Berthiaume,Bharath D. Nath,Arno W. Tilles,Mehmet Toner,Martin L. Yarmush +6 more
TL;DR: A recent review as mentioned in this paper describes the progress and remaining challenges that must be resolved in order to develop the next generation of implantable and extracorporeal devices for adjunct or temporary liver assist.