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Michael J. Pugia

Researcher at Bayer Corporation

Publications -  31
Citations -  748

Michael J. Pugia is an academic researcher from Bayer Corporation. The author has contributed to research in topics: Dipstick & Reagent. The author has an hindex of 15, co-authored 31 publications receiving 722 citations.

Papers
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Patent

Ascorbate resistant detection of hydrogen peroxide

TL;DR: In this paper, a method for the detection of hydrogen peroxide in biological fluids or an aqueous solution which involves contacting the solution with an oxidation-reduction indicator and a transition metal complex is presented.
Patent

System for creatinine determination

TL;DR: Disclosed as discussed by the authors is a dry reagent system involving an absorbent carrier incorporated with a dye precursor which undergoes a detectable response in the presence of creatinine under strongly basic conditions and also contains a moderating agent for the strong base which is a polyglycol or a polymerized quaternary ammonium salt.
Patent

Method for the determination of specific gravity of fluids

TL;DR: In this paper, a method and device for the determination of specific gravity in aqueous systems, particularly urine, was presented, which improves upon the known systems for detecting specific gravity by the use of a polyelectrolyte polymer and pH indicator by the addition of a crown ether ionophore which enhances the ability of the reagent system to indicate the fluid's specific gravity.
Patent

Trypsin substrate and diagnostic device, and method of using same

TL;DR: A compound of the formula (I) is a substrate such that trypsin cleaves the O-C single-bond, which liberates R 3 -OH as discussed by the authors.
Patent

Method for the detection of lysozyme

TL;DR: In this article, the use of alkyl sulfonic acids or sulfonates to increase both specificity and sensitivity of the reagent for lysozyme has been proposed to increase the sensitivity and specificity of the test.