M
Michael V. D’Ambrosio
Researcher at University of California, Berkeley
Publications - 18
Citations - 1357
Michael V. D’Ambrosio is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Loa loa & Lymphatic filariasis. The author has an hindex of 11, co-authored 16 publications receiving 807 citations. Previous affiliations of Michael V. D’Ambrosio include Swiss Tropical and Public Health Institute & Erasmus University Rotterdam.
Papers
More filters
Journal ArticleDOI
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy.
Parinaz Fozouni,Sungmin Son,María Díaz de León Derby,Gavin J. Knott,Gavin J. Knott,Carley N. Gray,Carley N. Gray,Michael V. D’Ambrosio,Chunyu Zhao,Neil A. Switz,G. Renuka Kumar,G. Renuka Kumar,Stephanie I. Stephens,Stephanie I. Stephens,Daniela Boehm,Daniela Boehm,Chia-Lin Tsou,Chia-Lin Tsou,Jeffrey Shu,Jeffrey Shu,Abdul Bhuiya,Maxim Armstrong,Andrew R. Harris,Pei Yi Chen,Pei Yi Chen,Jeannette M. Osterloh,Anke Meyer-Franke,Bastian Joehnk,Keith Walcott,Anita Sil,Charles Langelier,Katherine S. Pollard,Emily D. Crawford,Andreas S. Puschnik,Maira Phelps,Amy Kistler,Joseph L. DeRisi,Jennifer A. Doudna,Daniel A. Fletcher,Melanie Ott +39 more
TL;DR: This work reports the development of an amplification-free CRISPR-Cas13a assay for direct detection of SARS-CoV-2 from nasal swab RNA that can be read with a mobile phone microscope and has the potential to enable rapid, low-cost, point-of-care screening for Sars-Cov-2.
Journal ArticleDOI
Low-cost mobile phone microscopy with a reversed mobile phone camera lens.
TL;DR: A simple and low-cost approach to mobile phone microscopy that uses a reversed mobile phone camera lens added to an intact mobile phone to enable high quality imaging over a significantly larger field of view than standard microscopy is presented.
Journal ArticleDOI
Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope
Michael V. D’Ambrosio,Matthew H. Bakalar,Sasisekhar Bennuru,Clay D. Reber,Arunan Skandarajah,Lina Nilsson,Neil A. Switz,Joseph Kamgno,Sébastien D. S. Pion,Michel Boussinesq,Thomas B. Nutman,Daniel A. Fletcher +11 more
TL;DR: A mobile phone–based video microscope that automatically quantifies L. loa microfilariae in whole blood and excludes patients from ivermectin-based treatment at the point of care in Loa-endemic regions would allow resumption/expansion of mass drug administration programs for onchocerciasis and lymphatic filariasis in Central Africa.
Journal ArticleDOI
A Test-and-Not-Treat Strategy for Onchocerciasis in Loa loa–Endemic Areas
Joseph Kamgno,Sébastien D. S. Pion,Cédric B Chesnais,Matthew H. Bakalar,Michael V. D’Ambrosio,Charles D. Mackenzie,Hugues C. Nana-Djeunga,Raceline Gounoue-Kamkumo,Guy-Roger Njitchouang,Philippe Nwane,Jules B Tchatchueng-Mbouga,Samuel Wanji,Wilma A. Stolk,Daniel A. Fletcher,Amy D. Klion,Thomas B. Nutman,Michel Boussinesq +16 more
TL;DR: The LoaScope‐based test‐and‐not‐treat strategy enabled the reimplementation of community‐wide ivermectin distribution in a heretofore “off limits” health district in Cameroon and is a potentially practical approach to larger‐scale iverMectin treatment for lymphatic filariasis and onchocerciasis in areas where L. loa infection is endemic.
Journal ArticleDOI
Multi-Contrast Imaging and Digital Refocusing on a Mobile Microscope with a Domed LED Array
Zachary F. Phillips,Michael V. D’Ambrosio,Lei Tian,Jared J. Rulison,Hurshal S. Patel,Nitin Sadras,Aditya V. Gande,Neil A. Switz,Daniel A. Fletcher,Laura Waller +9 more
TL;DR: A digital refocusing procedure can be used for either 3D imaging or software-only focus correction, reducing the need for precise mechanical focusing during field experiments, and the performance of this add-on device is comparable to that of a commercial microscope.