Monica Biscaldi

TL;DR: Using exome sequencing, it is shown that analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry-matched or parental controls implicates 22 autosomal genes at a false discovery rate of < 0.05, plus a set of 107 genes strongly enriched for those likely to affect risk (FDR < 0.30).

TL;DR: The saccadic performance of a large number of subjects of different ages was studied applying two saccade tasks: the prosaccade overlap (PO) task and the antisaccade gap (AG) task, offering a detailed baseline for clinical studies using the pro- and antisaccades tasks as an indication of functional impairments, circumscribed brain lesions, neurological and psychiatric diseases and cognitive deficits.

TL;DR: The results suggest that, in the gap task, most of the naive subjects exhibit at least two clearly separated peaks in the distribution of the saccadic reaction times, which indicates that express saccades almost never overshoot.

TL;DR: The data support the hypothesis that there is a link between disturbances of the cingulate NAA and Glx metabolism, and autism, and the hypothesis of excitatory/inhibitory imbalance in autism is supported.

TL;DR: It is suggested that reading process and saccade system are both controlled by visuo spatial attention and fixation systems that maybe impaired or develop slowly in many dyslexic subjects.