M
Myriam Baes
Researcher at Katholieke Universiteit Leuven
Publications - 164
Citations - 9132
Myriam Baes is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Peroxisome & Zellweger syndrome. The author has an hindex of 44, co-authored 154 publications receiving 8242 citations. Previous affiliations of Myriam Baes include Catholic University of Leuven & Salk Institute for Biological Studies.
Papers
More filters
Journal ArticleDOI
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Stephane Heymans,Aernout Luttun,Dieter Nuyens,Gregor Theilmeier,Esther E. Creemers,Lieve Moons,G D Dyspersin,Jack P.M. Cleutjens,M Shipley,A Angellilo,Marcel Levi,O Nübe,Andrew Baker,Eli Keshet,Florea Lupu,Jean-Marc Herbert,Jos F.M. Smits,Steven D. Shapiro,Myriam Baes,Marcel Borgers,Desire Collen,Mat J.A.P. Daemen,Peter Carmeliet +22 more
TL;DR: Temporary administration of PA inhibitor-1 or the matrix metalloproteinase-inhibitor TIMP-1 completely protected wild-type mice against rupture but did not abort infarct healing, thus constituting a new approach to prevent cardiac rupture after acute myocardial infarction.
Journal ArticleDOI
Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation
Peter Carmeliet,Lieve Moons,Roger Lijnen,Myriam Baes,Vincent Lemaître,Peter G. Tipping,Angela Drew,Angela Drew,Yves Eeckhout,Steve Shapiro,Florea Lupu,Desire Collen +11 more
TL;DR: Analysis of atherosclerotic aorta in mice with a deficiency of apoliprotein E indicated that deficiency of u-PA protected against media destruction and aneurysm formation, probably by means of reduced plasmin-dependent activation of pro-MMPs.
Journal ArticleDOI
A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements.
TL;DR: It is proposed that MB67 plays an important role in the complex network of proteins that govern response to retinoic acid and its metabolites.
Journal ArticleDOI
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
Julián Aragonés,Martin Schneider,Martin Schneider,Martin Schneider,Katie Van Geyte,Katie Van Geyte,Peter Fraisl,Peter Fraisl,Tom Dresselaers,Massimiliano Mazzone,Massimiliano Mazzone,Ruud Dirkx,Serena Zacchigna,Serena Zacchigna,Hélène Lemieux,Nam Ho Jeoung,Diether Lambrechts,Diether Lambrechts,Tammie Bishop,Peggy Lafuste,Peggy Lafuste,Antonio Diez-Juan,Antonio Diez-Juan,Sarah K. Harten,Pieter Van Noten,Katrien De Bock,Carsten Willam,Marc Tjwa,Marc Tjwa,A. Grosfeld,Rachel Navet,Lieve Moons,Lieve Moons,Thierry VandenDriessche,Thierry VandenDriessche,Christophe Deroose,Bhathiya Wijeyekoon,Johan Nuyts,Bénédicte F. Jordan,Robert Silasi-Mansat,Florea Lupu,Mieke Dewerchin,Mieke Dewerchin,Christopher W. Pugh,Phil Salmon,Luc Mortelmans,Bernard Gallez,Frans Gorus,Johan Buyse,Francis Sluse,Robert A. Harris,Erich Gnaiger,Peter Hespel,Paul Van Hecke,Frans Schuit,Paul P. Van Veldhoven,Peter J. Ratcliffe,Myriam Baes,Patrick H. Maxwell,Peter Carmeliet,Peter Carmeliet +60 more
TL;DR: It is shown that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparα pathway.
Journal ArticleDOI
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Sandra Schoors,Ulrike Bruning,Rindert Missiaen,Karla C. S. Queiroz,Gitte Borgers,Ilaria Elia,Annalisa Zecchin,Anna Rita Cantelmo,Stefan Christen,Jermaine Goveia,Ward Heggermont,Lucica Godde,Stefan Vinckier,Paul P. Van Veldhoven,Guy Eelen,Luc Schoonjans,Holger Gerhardt,Mieke Dewerchin,Myriam Baes,Katrien De Bock,Bart Ghesquière,Sophia Y. Lunt,Sarah-Maria Fendt,Peter Carmeliet +23 more
TL;DR: It is reported that endothelial loss of CPT1A, a rate-limiting enzyme of fatty acid oxidation (FAO), causes vascular sprouting defects due to impaired proliferation, not migration, of human and murine endothelial cells.